Results 241 to 250 of about 66,236 (336)

Transinactivation of the epidermal growth factor receptor tyrosine kinase and focal adhesion kinase phosphorylation by dietary flavonoids: effect on invasive potential of human carcinoma cells.

Biochemical Pharmacology, 2004
Lung-Ta Lee, Ying‐tang Huang, Jiuan-Jiuan Hwang, A. Lee, F. Ke, Chang-jen Huang, C. Kandaswami, P. Lee, Ming‐ting Lee   +8 more
semanticscholar   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

LYN mutations in breast cancer: hypothesis-generating evidence for an association with central nervous system metastasis and domain-level insights. [PDF]

BMC Cancer
Çağdaş EK, Çağdaş B.
europepmc   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Decoding collagen cues: the interplay of integrins and discoidin domain receptors in health and disease. [PDF]

J Biomed Sci
Trono P, Masi I, Ottavi F, Rosanò L.
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Molecular basis and cellular effects of Janus-class-driven cytoplasmic PYK2 coacervates. [PDF]

Commun Biol
Colombo G, Salem I, Szczepski K, Yu P, Alfaiyz S, Guzmán-Vega FJ, Abogosh A, Kulmanov M, Al-Harthi S, Kadaré G, Hoehndorf R, Girault JA, Jaremko Ł, Momin AA, Arold ST.   +14 more
europepmc   +1 more source

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK

Molecular and Cellular Biology, 1995
B. Eide, C. Turck, J. Escobedo
semanticscholar   +1 more source

PFAS properties and destruction methods: A focus on enzymatic degradation

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Per‐ and polyfluoroalkyl substances (PFAS) are known as ‘forever’ chemicals and have lasting detrimental impact on the environment and living organisms. To understand PFAS molecules better, this review begins with an overview of PFAS definition, classifications and applications, and then provides a comprehensive summary and critical analysis ...
Guobin Liang, Hua Zhao
wiley   +1 more source

The LNK adaptor protein: a dual regulator of proliferation and migration in solid tumors. [PDF]

Mol Cell Oncol
Mantilla-Ollarves JC, Velazquez L, Rocha-Zavaleta L.   +2 more
europepmc   +1 more source