Results 221 to 230 of about 25,880 (235)

Abstract A249: BI 853520, a potent and highly selective inhibitor of protein tyrosine kinase 2 (focal adhesion kinase), shows efficacy in multiple xenograft models of human cancer.

Molecular Cancer Therapeutics, 2011
Abstract PTK2/FAK is a widely expressed non-receptor tyrosine kinase located mainly at focal adhesions. Sensing upstream signals from growth factor receptors as well as integrins, the enzyme contributes to activation of multiple downstream signaling pathways involved in the regulation of cell survival, proliferation and motility.
Ulrich A. Hirt, Juergen Braunger, Michael Schleicher, Ulrike Weyer-Czernilofsky, Pilar Garin-Chesa, Bojan Bister, Heinz Stadtmueller, Ioannis Sapountzis, Norbert Kraut, Guenther R. Adolf   +9 more
openaire   +1 more source

Focal Adhesion Kinase and Associated Proteins

Current Opinion in Cell Biology, 1994
J T Parsons, J Thomas Parsons, M D Schaller   +2 more
exaly  

Focal Adhesion Kinase: In Command and Control of Cell Motility

Nature Reviews Molecular Cell Biology, 2005
David Schlaepfer
exaly  

Nitric Oxide Stimulates Tyrosine Phosphorylation of Focal Adhesion Kinase, SRC Kinase, and Mitogen-Activated Protein Kinases in Murine Fibroblasts

Free Radical Biology and Medicine, 2000
Hugo P Monteiro, Arnold Stern, A Stern
exaly  

Src Family Protein Tyrosine Kinases: Cooperating With Growth Factor and Adhesion Signaling Pathways

Current Opinion in Cell Biology, 1997
Sarah J Parsons, J T Parsons, J Thomas Parsons   +2 more
exaly  

The Association of Focal Adhesion Kinase With a 200-kDa Protein That Is Tyrosine Phosphorylated in Response to Platelet-Derived Growth Factor

FEBS Journal, 1996
Jun-Lin Guan, Hong-Chen Chen, J L Guan
exaly  

Characterization of RAFTK, a Novel Focal Adhesion Kinase, and Its Integrin-Dependent Phosphorylation and Activation in Megakaryocytes

Blood, 1996
Hava Karsenty Avraham, R A Rogers, S Avraham   +2 more
exaly  

Lysophosphatidic Acid Induces Tyrosine Phosphorylation and Activation of MAP-Kinase and Focal Adhesion Kinase in Cultured Swiss 3T3 Cells

FEBS Letters, 1993
Shuh Narumiya, Takaaki Yoshimasa, Kazuko Fujisawa   +2 more
exaly  

C-Src Tyrosine Phosphorylation of Epidermal Growth Factor Receptor, P190 RhoGAP, and Focal Adhesion Kinase Regulates Diverse Cellular Processes

Chemical Reviews, 2001
Sarah J Parsons, J T Parsons, J Thomas Parsons   +2 more
exaly  

Src-Mediated Tyrosine Phosphorylation of Protein Kinase D2 at Focal Adhesions Regulates Cell Adhesion

Scientific Reports, 2017
Tim Eiseler, Peter Storz, Heike Döppler
exaly