Results 211 to 220 of about 66,236 (336)

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Macrophage-associated kinase signaling in atherosclerosis - a systematic review. [PDF]

Cell Commun Signal
Müller JS, van der Vorst EPC.
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Anoikis: To Die or Not to Die? [PDF]

Int J Mol Sci
Koltai T, Fliegel L.
europepmc   +1 more source

Pyk2 and Src‐family protein‐tyrosine kinases compensate for the loss of FAK in fibronectin‐stimulated signaling events but Pyk2 does not fully function to enhance FAK− cell migration

EMBO Journal, 1998
David J. Sieg, D. Ilić, K.C. Jones, C. Damsky, T. Hunter, D. Schlaepfer   +5 more
semanticscholar   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Loss of ROR2 Tyrosine Kinase Receptor Is Associated With Endothelial Dysfunction in PAH via Inappropriate Integrin β1 Activation. [PDF]

Hypertension
Mitra A, Agarwal S, Chakraborty A, Zhong BL, Heo L, Roy A, Bankar A, Pacheco A, Auer N, Dunn A, Chelladurai P, Jain A, Matos Muñoz JA, Guardado ES, Yi D, Zhao H, Man KWD, Nair R, Hong J, Kuebler WM, Guenat OT, Dai Z, de Jesus Perez VA.   +22 more
europepmc   +1 more source

Protein Tyrosine Phosphatase α Phosphotyrosyl-789 Binds BCAR3 To Position Cas for Activation at Integrin-Mediated Focal Adhesions

Molecular and Cellular Biology, 2012
Guobin Sun, Suzanne Y. S. Cheng, Min Chen, C. Lim, C. Pallen   +4 more
semanticscholar   +1 more source

Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton

, 1993
James Sinnett‐Smith, Ian Zachary, Ángela M. Valverde, Enrique Rozengurt   +3 more
openalex   +1 more source

Focal adhesion kinase: A promising regulator of colitis-associated healing. [PDF]

World J Gastroenterol
Malek KK, Kumar B, Ahmad R, Singh A, Basson MD.   +4 more
europepmc   +1 more source