Results 201 to 210 of about 25,880 (235)

The PD-L1-mTOR intersection in tumor migration and invasion. [PDF]

Mol Biol Rep
Palavro R, Previato TTR, Pazzin DB, Gonçalves JB, Boff MO, Marinowic D, da Costa JC, Scheffel TB.   +7 more
europepmc   +1 more source

Multi‐Omics Integration Reveals Metabolic Reprogramming and EMT‐Driven Metastasis in Triple‐Negative Breast Cancer

Cancer Science, EarlyView.
Integrated transcriptomic, metabolomic, and spatial proteomic profiling of TNBC tumors identifies a metastatic‐associated molecular landscape characterized by EMT activation, metabolic reprogramming, and tumor microenvironment (TME) remodeling. Multi‐omics integration reveals coordinated alterations in EMT signatures, amino acid metabolism, immune ...
Yuheng Pang, Yuefeng Shang, Wenjing Wang, Tong Liu, Xiaolong Zou   +4 more
wiley   +1 more source

Roles of integrin β1 and discoidin domain receptor 2 in cranial regeneration and skeletal progenitor cell function. [PDF]

Int J Oral Sci
Han Y, Ge C, Kamath RA, Kaartinen V, Franceschi RT.   +4 more
europepmc   +1 more source

Unresolved mechanisms: a hypothesized spatial regulation of myosin light chain phosphorylation within the walls of resistance arteries. [PDF]

Front Physiol
Sun Z, Hill MA.
europepmc   +1 more source

Towards an integrative structural model of the fishnet slit diaphragm: Understanding its physiology through proteomics and structural insight. [PDF]

Pflugers Arch
Frangakis AS, Birtasu AN, Grahammer F.
europepmc   +1 more source

The role of ECM mechanics in cancer mechanotransduction through unraveling the molecular machinery of integrins, FAK, and YAP signaling. [PDF]

Cell Mol Biol Lett
Hassan N, Greve B, Götte M.
europepmc   +1 more source

Expression of Concern: Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats. [PDF]

J Am Heart Assoc
europepmc   +1 more source

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Overexpression of Focal Adhesion Kinase, a Protein Tyrosine Kinase, in Ovarian Carcinoma

Cancer, 1999
Focal adhesion kinase (FAK) is a tyrosine kinase that is important to such key functions such as cell adhesion, motility, and invasion. A MEDLINE search of the years 1980-1998 found no previous reports of FAK expression in human ovarian carcinoma. The authors performed experiments to determine whether FAK expression is elevated in this disease.Ten ...
Xiaping He, W G Cance, William G Cance
exaly   +3 more sources

Interactions of the Protein-Tyrosine Phosphatase-α With the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Are Involved in Interleukin-1 Signaling in Fibroblasts [PDF]

Journal of Biological Chemistry, 2014
Interleukin-1 (IL-1) signaling in fibroblasts is mediated through focal adhesions, organelles that are enriched with adaptor and cytoskeletal proteins that regulate signal transduction. We examined interactions of the focal adhesion kinase (FAK) with protein-tyrosine phosphatase-α (PTP-α) in IL-1 signaling.
Dhaarmini Rajshankar, Christopher McCulloch, Yongqiang Wang   +2 more
exaly   +3 more sources