Results 101 to 110 of about 713,420 (262)

Focal cortical dysplasia with prolonged ictal asystole, a case report [PDF]

, 2020
Introduction: Cortical dysplasia carries significant morbidities such as seizures and delayed milestones. Focal cortical dysplasia (FCD) causes refractory epilepsy with various seizure types depending on the location and extent of the dysplasia.
Siddiqui, Fowzia, Wali, Ahmad
core  

9.4‐Tesla magnetic resonance imaging in focal epilepsy patients with high‐resolution surface‐based profiling of focal cortical dysplasias

Epilepsia, EarlyView.
Abstract Objective The detection of subtle epileptogenic lesions such as focal cortical dysplasias (FCDs) is a clinical challenge in the management of drug‐resistant focal epilepsy (DRFE). Ultra‐high‐field (UHF) magnetic resonance imaging (MRI) offers increased signal‐to‐noise ratios and spatial resolution compared to 3‐T MRI and may improve diagnostic
Cornelius Kronlage, Pascal Martin, Benjamin Bender, Gisela E. Hagberg, Jonas Bause, Joana R. A. Loureiro, Mathilde Ripart, Sophie Adler, Konrad Wagstyl, Holger Lerche, Niels K. N. Focke, Esther Kuehn   +11 more
wiley   +1 more source

Adult-onset epilepsy in focal cortical dysplasia of Taylor type.

, 2005
Focal cortical dysplasia of Taylor type (FCDT) usually presents with seizures at an early age, whereas adult onset of epilepsy is uncommon. We reviewed the medical records of 213 patients with FCDT.
Devinsky O, Cossu M, Urbach H, Siegel AM, Najjar S, Dubeau F, LoRusso G, Scheithauer BW, Aronica E, Andermann F, Meyer FB, Cascino GD, Elger CE, Laff R, Sperling MR   +14 more
core   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

Epilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Cortical neuronal densities and lamination in focal cortical dysplasia.

, 2005
Focal cortical dysplasia (FCD) is considered to represent a malformation due to abnormal cortical development (MCD) and is an important cause of focal epilepsy.
Martinian, L, Sisodiya, SM, Sen, A, Thom, M, Sen, Arjune, Cross, JH, Harding, BN   +6 more
core   +1 more source

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo, Lirong Han, Nicholas R. Rensing, Laura A. Jansen, Michael Wong   +4 more
wiley   +1 more source

Focal cortical dysplasia lesion segmentation using multiscale transformer

Insights into Imaging
Objectives Accurate segmentation of focal cortical dysplasia (FCD) lesions from MR images plays an important role in surgical planning and decision but is still challenging for radiologists and clinicians.
Xiaodong Zhang, Yongquan Zhang, Changmiao Wang, Lin Li, Fengjun Zhu, Yang Sun, Tong Mo, Qingmao Hu, Jinping Xu, Dezhi Cao   +9 more
doaj   +1 more source

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement

Nature Communications, 2016
The etiology of focal cortical dysplasia (FCD) is not fully understood. Here authors generate an mTORC1 overactivation mouse model that recapitulates hallmarks of type II FCDs, including spontaneous seizures, and suggest that neuronal defects, rather ...
Lawrence S. Hsieh, John H. Wen, Kumiko Claycomb, Yuegao Huang, Felicia A. Harrsch, Janice R. Naegele, Fahmeed Hyder, Gordon F. Buchanan, Angelique Bordey   +8 more
doaj   +1 more source

Comparison of clinical features and surgical outcome in focal cortical dysplasia type 1 and type 2

, 2017
Introduction: Recent ILAE classification defined focal cortical dysplasia (FCD) patients with accompanying epileptic lesions as a separate group. We investigated data of patients with sole FCD lesions regarding long-term seizure outcome and different ...
IS, Merih, Uzan, Mustafa, Tanriverdi, Taller, Isler, Cihan, Ozkara, Cigdem, Kucukyuruk, Bans, Gunduz, Aysegul, Oz, Buge, Comunoglu, Nil, Cihan Isler, Nil Comunoglu, Buge Oz, Tanriverdi, Taner, Mustafa Uzan, Kucukyuruk, Barış, Baris Kucukyuruk, Taner Tanriverdi, Aysegul Gunduz, Cigdem Ozkara, Merih Is   +19 more
core   +1 more source