Results 111 to 120 of about 50,276 (321)
Acta Médica Portuguesa, 2001 This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%.
S Carvalho +8 more
doaj +1 more source
Resolution of generalized tonic seizures following focal ablative or resective surgery
Epileptic Disorders, EarlyView.Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman +3 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract Objective For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,
Naotaka Usui +11 more
wiley +1 more source
Surgical Management of Seizures with Focal Cortical Dysplasia
Pediatric Neurology Briefs, 2003 Anatomical-clinical correlations and EEG findings in 10 children, aged 26 months to 11 years (median 6 years), with drug resistant partial epilepsy and focal cortical dysplasia, operated on 1996-2000, were analysed at the Epilepsy Surgery Centre “C ...
J Gordon Millichap
doaj +1 more source
CEDNIK: Phenotypic and molecular characterization of an additional patient and review of the literature [PDF]
, 2017 Synaptosomal-associated protein 29 (SNAP29) is a t-SNARE protein that is implicated in intracellular vesicle fusion. Mutations in the SNAP29 gene have been associated with cerebral dysgenesis, neuropathy, ichthyosis, and keratoderma syndrome (CEDNIK). In
Coughlin, Carrie C +6 more
core +3 more sources
Epileptic Disorders, EarlyView.Abstract Objective This study aimed to evaluate the usefulness of intraoperative electrocorticography (iECoG) in providing a more accurate surgical strategy, thereby yielding seizure freedom following resective surgery in children with temporal lobe epilepsy (TLE).
Rafael Andrade Cruz +8 more
wiley +1 more source
mTOR pathway inhibition as a new therapeutic strategy in epilepsy and epileptogenesis. [PDF]
, 2016 Several preclinical and some clinical studies have revealed that the mammalian target of rapamycin (mTOR) signaling pathway is involved in both genetic and acquired epilepsy syndromes.
Citraro, R +4 more
core +1 more source
Epileptic Disorders, EarlyView.Abstract Epilepsy surgery remains the most effective treatment for focal drug‐resistant epilepsy, and stereoelectroencephalography (SEEG) is increasingly used to define the epileptogenic‐zone network (EZN) and guide curative or palliative interventions.
Ionuț‐Flavius Bratu +4 more
wiley +1 more source
Pediatric Neurology Briefs, 2012 Researchers at University of Southampton, UK report an infant with focal seizures secondary to cortical dysplasia who presented at age 4 months with bilateral pinpoint pupils as first feature of right-sided clonic seizure.
J Gordon Millichap
doaj +1 more source
Эпилепсия и пароксизмальные состояния, 2020 Introduction. The cessation of epileptic seizures after surgical treatment of focal epilepsy is the main objective of the surgeon. When a neurosurgeon operates focal cortical dysplasia (FCD), he/she faces difficulties with the radical removal of ...
A. A. Sufianov +8 more
doaj +1 more source