Results 131 to 140 of about 713,420 (262)

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

Epilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis, Douglas R. Nordli Jr., Douglas R. Nordli III, Shlomo Shinnar, Stephen Chan, Jacqueline A. Bello, L. Matthew Frank, James Voyvodic, William Gallentine, Syndi Seinfeld, Yoshimi Sogawa, Erica Weiss, David Masur, Yuan Xu, Solomon L. Moshé   +14 more
wiley   +1 more source

Seven tesla MRI improves detection of focal cortical dysplasia in patients with refractory focal epilepsy

, 2017
Objective: The aim of this study is to determine whether the use of 7 tesla (T) MRI in clinical practice leads to higher detection rates of focal cortical dysplasias in possible candidates for epilepsy surgery.
Veersema, Tim J, Hendrikse, Jeroen, Visser, Fredy, Braun, Kees P J, Aronica, Eleonora, Luijten, Peter R, van Eijsden, Pieter, Gosselaar, Peter H, Ferrier, Cyrille H, Zwanenburg, Jaco M, de Kort, Gerard A P, Regenerative Medicine and Stem Cells, Brain, Zorglijn FNE Medisch, Researchgr. Neuroradiologie, Pathologie, ZL Algemene en Acute Nec Medisch, MS Radiologie, ZL Kinder Ner en Nec Medisch, Circulatory Health, Divisie Beeld, Cancer, Highfield Research Group   +22 more
core  

AI‐based localization of the epileptogenic zone using intracranial EEG

Epilepsia Open, EarlyView.
Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida, Yipeng Zhang, Sotaro Kanai, Richard Staba, Vwani Roychowdhury, Hiroki Nariai   +5 more
wiley   +1 more source

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source

Stability of the Epileptogenic Index across seizures and the effects of sleep and withdrawal of anti‐seizure medications

Epilepsia Open, EarlyView.
Abstract Objective Epileptogenic Index (EI) is a promising index to evaluate the epileptogenicity of the brain tissue and is useful in planning epilepsy surgery. We aimed to evaluate whether EI maps are consistent across seizures within patients and whether EI‐derived measures are affected by the vigilance state and anti‐seizure medication (ASM) dose ...
May Bar‐On, Noam Ben‐Eliezer, Noam Fallik, Lilac Goldstein, Guy Gurevitch, Ido Strauss, Inbal Maidan, Firas Fahoum   +7 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation in drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial with exploratory EEG and MRI response phenotyping

Epilepsia Open, EarlyView.
Abstract Objective Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive neuromodulation strategy for drug‐resistant epilepsy, but clinical response is heterogeneous. We examined whether electroencephalographic (EEG) and structural magnetic resonance imaging (MRI) phenotypes were associated with active‐specific clinical benefit from
Sung Jun Hong, Seok‐Yeol Yang, Eun Kyung Bok, Jung Chul Lee, Yeonggin Kim, Kyousik Min, Young‐Min Shon   +6 more
wiley   +1 more source

Deep tissue sequencing improves genetic diagnostic yield in focal cortical dysplasia. [PDF]

Prog Neuropsychopharmacol Biol Psychiatry
Galea B, Reid J, Gooley S, Witkowski T, Lane T, Macdonald S, Green TE, Ye Z, Adikari T, Bulluss K, Mullen SA, Bennett CA, Forster B, Bradshaw G, Lin W, De Silva W, Ramirez RB, Khoshkhoo S, Gupta S, Krivanek M, Kothur K, Gill D, Pope K, Gillies G, Coleman M, Lee WS, Stephenson SM, Maixner W, Harvey AS, Macdonald-Laurs E, Howell KB, D'Arcy C, Lockhart PJ, Leventer RJ, Kalnins RM, Clark J, Bennett MF, Bahlo M, Scheffer IE, Perucca P, Berkovic SF, Hildebrand MS.   +41 more
europepmc   +2 more sources

Early neurocognitive outcomes following SEEG with radiofrequency thermocoagulation

Epilepsia Open, EarlyView.
Abstract Objective Characterization of early neuropsychological outcomes following SEEG with radiofrequency thermocoagulation (RFTHC) is essential to guide patient expectations around return to work, study, and caregiving. The current study aimed to describe the early neurocognitive sequelae of SEEG.
Emily Cockle, Charles B. Malpas, Honor Coleman, Alissandra McIlroy, Joshua Laing, Martin Hunn, Matthew Gutman, Stacey Logan, Georgia‐Rose Robinson, Cecilia Harb, Catherine Meade, Wendyl D'Souza, Amy Halliday, Kristian Bulluss, Simon Vogrin, Rubina Alpitsis, Terence J. O'Brien, Genevieve Rayner, Andrew Neal   +18 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source