Results 1 to 10 of about 2,059 (132)

Folate Receptor Beta Signaling in the Regulation of Macrophage Antimicrobial Immune Response: A Scoping Review [PDF]

Biomedicine Hub
Introduction: Folate, vitamin B9, is a water-soluble vitamin that is essential to cellular proliferation and division. In addition to the reduced folate carrier, eukaryotic cells take up folate through endocytosis mediated by one of two GPI-anchored ...
Anna C.C. Castelo Branco, Lisa M. Rogers, David M. Aronoff   +2 more
doaj   +2 more sources

Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection. [PDF]

, 2014
International audienceHepatitis C virus (HCV) establishes infection using host lipid metabolism pathways that are thus considered potential targets for indirect anti-HCV strategies. HCV enters the cell via clathrin-dependent endocytosis, interacting with
Bocchetta, Simone, Bourgine, Maryline, Budkowska, Agata, Douam, Florian, Gondeau, Claire, Guérin, Maryse, Helle, François, Lagaye, Sylvie, Lavillette, Dimitri, Le Goff, Wilfried, Lebreton, Stéphanie, Louise Michel, Marie, Maillard, Patrick, Plengpanich, Wanee, Pol, Stanislas, Roingeard, Philippe, Yamamoto, Mami   +16 more
core   +10 more sources

siRNA inhibition of endocytic pathways to characterize the cellular uptake mechanisms of folate-functionalized glycol chitosan nanogels [PDF]

, 2015
Glycol chitosan nanogels have been widely used in gene, drug, and contrast agent delivery in an effort to improve disease diagnosis and treatment. Herein, we evaluate the internalization mechanisms and intracellular fate of previously described glycol ...
Correia, Alexandra, Gama, F. M., Jones, Arwin T., Pedrosa, Sílvia Santos, Pereira, Paula, Sayers, Edward, Vilanova, Manuel, Wymant, Jennifer M.   +7 more
core   +2 more sources

Identification of a target protein of Hydra actinoporin-like toxin-1 (HALT-1)using GST affinity purification and SILAC-based quantitative proteomics [PDF]

, 2017
Hydra actinoporin-like toxin-1 (HALT-1) is a 20.8 kDa pore-forming toxin isolated from Hydra magnipapillata. HALT-1 shares structural similarity with actinoporins, a family that is well known for its haemolytic and cytolytic activity.
Ameirika, ., Hong, Xi Sha, Hwang, Jung Shan *   +2 more
core   +1 more source

Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele. [PDF]

, 2010
BACKGROUND: Meningomyelocele (MM) results from lack of closure of the neural tube during embryologic development. Periconceptional folic acid supplementation is a modifier of MM risk in humans, leading toan interest in the folate transport genes as ...
Au, Kit Sing, Doebel, Sabine, Fletcher, Jack M, Lin, Jone-Ing, Morrison, Alanna C, Northrup, Hope, O\u27Byrne, Michelle R, Ostermaier, Kathryn K, Tyerman, Gayle H   +8 more
core   +1 more source

Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]

, 2010
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core   +1 more source

Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]

, 2010
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido, Baraniskin, Alexander, Jähnert, Andreas, Kretzschmar, Hans, Schmiegel, Wolff, Schroers, Roland, Theile, Anja   +6 more
core   +1 more source

Human NKG2D-ligands: cell biology strategies to ensure immune recognition [PDF]

, 2012
Immune recognition mediated by the activating receptor NKG2D plays an important role for the elimination of stressed cells, including tumors and virus-infected cells.
Hugh T. Reyburn, Lola Fernández-Messina, Mar Valés-Gómez   +2 more
core   +2 more sources

Inhibition of bispecific monoclonal antibody (bsAb)-targeted cytolysis by human anti-mouse antibodies in ovarian carcinoma patients treated with bsAb-targeted activated T-lymphocytes [PDF]

, 1995
T lymphocytes of 8 patients with ovarian cancer were targeted to the tumor cells using F(ab')2 fragments of a bispecific monoclonal antibody (bsAb), specific for CD3 (a component of the T lymphocyte receptor for antigen) and for the folate receptor MOv ...
Bolhuis, R.L.H. (Reinder), Gratama, J.W. (Jan-Willem), Lamers, C.H.J. (Cor), Stoter, G. (Gerrit), Warnaar, S.O. (Sven)   +4 more
core   +5 more sources

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]

, 1999
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Oliferenko, S., Paiha, K., Harder, T., Gerke, V., Schwärzler, C., Schwarz, H., Beug, H., Günthert, U., Huber, L. A.   +8 more
core   +1 more source