Results 91 to 100 of about 217,044 (288)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Folding models for elastic and inelastic scattering [PDF]
, 2005 The most widely used models are the optical model potential (OMP) for elastic scattering, and its generalization to non-spherical shapes, the deformed optical model potential (DOMP) for inelastic scattering. These models are simple and phenomenological; their parameters are adjusted so as to reproduce empirical data. Nonetheless, there are certain, not
openaire +1 more source
Does a Simple Lattice Protein Folding Model Exhibit Self-Organized Criticality? [PDF]
, 2014 Proteins are known to fold into tertiary structures that determine their functionality in living organisms. However, the way they consistently fold to the same structure is unknown.
Bajracharya, Arun +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Hindrance of the excitation of the Hoyle state and the ghost of the $2^+_2$ state in $^{12}$C
, 2010 While the Hoyle state (the isoscalar $0^+_2$ excitation at 7.65 MeV in $^{12}$C) has been observed in almost all the electron and $\alpha$ inelastic scattering experiments, the second $2^+$ excited state of $^{12}$C at $E_{\rm x}\approx 10$ MeV, believed
Ajenberg-Selove +44 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Combining Coarse-Grained Simulations and Single Molecule Analysis Reveals a Three-State Folding Model of the Guanidine-II Riboswitch. [PDF]
Front Mol Biosci, 2022 Fuks C +3 more
europepmc +1 more source
Export of miRNAs from activated macrophages is cooperative and HuR‐dependent
FEBS Letters, EarlyView.This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh +2 more
wiley +1 more source
Probing the isoscalar excitations of 12C with inelastic alpha scattering
, 2008 The robust (spin and isospin zero) $\alpha$-particle remains one of the best projectiles to probe the nuclear isoscalar excitations. In the present work, a microscopic folding model analysis of the \ac inelastic scattering to the 2$^+$ (4.44 MeV), 0$^+$ (
DAO T. KHOA, Satchler G. R.
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source