Results 111 to 120 of about 220,518 (289)

Repulsive nature of optical potentials for high-energy heavy-ion scattering

, 2010
The recent works by the present authors predicted that the real part of heavy-ion optical potentials changes its character from attraction to repulsion around the incident energy per nucleon E/A = 200 - 300 MeV on the basis of the complex G-matrix ...
Furumoto, T., Sakuragi, Y., Yamamoto, Y.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The optical potential of $^{6}$He in the eikonal approximation

, 2003
The new data of the elastic scattering of $^{6}$He+$^{12}$C at about 40 MeV/nucleon are analyzed in the eikonal approximation. The $^{6}$He+$^{12}$C phase-shift function is evaluated completely without any {\it ad hoc} assumption by a Monte Carlo ...
Abu-Ibrahim, Abu-Ibrahim, Abu-Ibrahim, Al-Khalili, Al-Khalili, Al-Khalili, Al-Khalili, Arai, B. Abu-Ibrahim, Becchetti, Bertsch, Blumberg, Bonaccorso, Brooke, Carlson, Cooper, Czyz, Esbensen, Fannon, Franco, Glauber, Lapoux, Lenzi, Pieper, Pudliner, Rapaport, Rusek, Sakuragi, Satchler, Suzuki, Suzuki, Tatischeff, Thompson, Varga, Wiringa, Y. Suzuki, Yabana   +36 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

FoldPAthreader: predicting protein folding pathway using a novel folding force field model derived from known protein universe

Genome Biology
Protein folding has become a tractable problem with the significant advances in deep learning-driven protein structure prediction. Here we propose FoldPAthreader, a protein folding pathway prediction method that uses a novel folding force field model by ...
Kailong Zhao, Pengxin Zhao, Suhui Wang, Yuhao Xia, Guijun Zhang   +4 more
doaj   +1 more source

Finite element analysis of the folding process of creased white-coated paperboard using a combined fluffing resistance and shear yield glue model

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
This study aims to develop a numerical simulation model of the folding process of a creased paperboard and to reveal the deformation characteristics of the creased paperboard.
Weerayut JINA, Shigeru NAGASAWA
doaj   +1 more source

Binding of charmonium with two- and three-body nuclei

, 2006
The energies of the (eta_c d) and (eta_c 3He) bound states are calculated on the basis of exact three- and four-body AGS equations. For the eta_c N interaction a Yukawa-type potential has been adopted. The calculations are done for a certain range of its
A. Fix, Alt, Alt, Belyaev, Brodsky, Brodsky, Cabrera, de Téramond, Donnachie, Fix, Fix, Fix, Garcilazo, Grassberger, Green, Harms, Kaiser, Lovelace, Luke, Mosel, N.V. Shevchenko, Oller, Pfeiffer, Rapp, Sandhas, Shevchenko, Sofianos, Tsushima, V.B. Belyaev, W. Sandhas, Wasson, Zankel   +31 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

How the cortex gets its folds: an inside-out, connectivity-driven model for the scaling of mammalian cortical folding

Frontiers in Neuroanatomy, 2012
Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the grey matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by ...
Bruno eMota, Bruno eMota, Suzana eHerculano-Houzel, Suzana eHerculano-Houzel   +3 more
doaj   +1 more source