Results 101 to 110 of about 217,044 (288)

Folding model analysis of $ ^{12}C- ^{12}C $ and $ ^{16}O- ^{16}O $ elastic scattering using the density-dependent LOCV averaged effective interaction

, 2018
The averaged effective two-body interaction (\textit{AEI}) which can be generated through the lowest order constrained variational (\textit{LOCV}) method for symmetric nuclear matter (\textit{SNM}) with the input \textit{Reid}68 nucleon-nucleon potential,
Modarres, M., Rahmat, M.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

FoldPAthreader: predicting protein folding pathway using a novel folding force field model derived from known protein universe

Genome Biology
Protein folding has become a tractable problem with the significant advances in deep learning-driven protein structure prediction. Here we propose FoldPAthreader, a protein folding pathway prediction method that uses a novel folding force field model by ...
Kailong Zhao, Pengxin Zhao, Suhui Wang, Yuhao Xia, Guijun Zhang   +4 more
doaj   +1 more source

Finite element analysis of the folding process of creased white-coated paperboard using a combined fluffing resistance and shear yield glue model

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
This study aims to develop a numerical simulation model of the folding process of a creased paperboard and to reveal the deformation characteristics of the creased paperboard.
Weerayut JINA, Shigeru NAGASAWA
doaj   +1 more source

Repulsive nature of optical potentials for high-energy heavy-ion scattering

, 2010
The recent works by the present authors predicted that the real part of heavy-ion optical potentials changes its character from attraction to repulsion around the incident energy per nucleon E/A = 200 - 300 MeV on the basis of the complex G-matrix ...
Furumoto, T., Sakuragi, Y., Yamamoto, Y.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

How the cortex gets its folds: an inside-out, connectivity-driven model for the scaling of mammalian cortical folding

Frontiers in Neuroanatomy, 2012
Larger mammalian cerebral cortices tend to have increasingly folded surfaces, often considered to result from the lateral expansion of the grey matter (GM), which, in a volume constrained by the cranium, causes mechanical compression that is relieved by ...
Bruno eMota, Bruno eMota, Suzana eHerculano-Houzel, Suzana eHerculano-Houzel   +3 more
doaj   +1 more source

Study of in-medium $\omega$ meson properties in Ap, pA and AA collisions

, 2008
We propose to investigate the in-medium properties of vector $\omega$ mesons at the normal nuclear density in Ap(pA) collisions and at higher density in AA collisions at the ITEP accelerator facility TWAC.
A. K. Dutt-Mazumder, B. Nilsson-Almqvist, D. Cabrera, D. Trnka, E. Ya. Paryev, F. Klingl, G. Agakichiev, G. E. Brown, G. I. Lykasov, H. Sorge, J. Adams, J. G. Messchendorp, K. Saito, K. Tsushima, K. Tsushima, M. F. M. Lutz, M. H. Wood, M. Kaskulov, M. Kotulla, M. M. Chumakov, M. Naruki, P. G. Reinhard, P. Muehlich, P. Muehlich, P. Muehlich, R. Novotny, S. Leupold, S. M. Kiselev, S. Zschocke, T. Hatsuda, T. Ishikawa, U. Mosel, V. Bernard, V. K. Magas, V. V. Barmin, W. Weise, Yu. T. Kiselev, Yu. T. Kiselev   +37 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source