Results 121 to 130 of about 217,044 (288)

Synthetic, Multi-Layer, Self-Oscillating Vocal Fold Model Fabrication

open access: yesJournal of Visualized Experiments, 2011
Sound for the human voice is produced via flow-induced vocal fold vibration. The vocal folds consist of several layers of tissue, each with differing material properties. Normal voice production relies on healthy tissue and vocal folds, and occurs as a result of complex coupling between aerodynamic, structural dynamic, and acoustic physical phenomena ...
Preston R, Murray, Scott L, Thomson
openaire   +3 more sources

Probing Correlated Ground States with Microscopic Optical Model for Nucleon Scattering off Doubly-Closed-Shell Nuclei

open access: yes, 2005
The RPA long range correlations are known to play a significant role in understanding the depletion of single particle-hole states observed in (e, e') and (e, e'p) measurements.
C. Mahaux   +14 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Mechanism of DNA origami folding elucidated by mesoscopic simulations

open access: yesNature Communications
Many experimental and computational efforts have sought to understand DNA origami folding, but the time and length scales of this process pose significant challenges.
Marcello DeLuca   +6 more
doaj   +1 more source

Between Realism and Non-Cognitivism in Ethics, A Three-Fold-Model. A Three-Fold-Model [PDF]

open access: yes, 2011
The aim of the paper is to propose an alternative model to realist and non-cognitive explanations of the rule-guided use of thick ethical concepts and to examine the implications that may be drawn from this and similar cases for our general understanding of rule-following and the relation between criteria of ap- plication, truth and correctness.
openaire  

Determination of Li-6 -- He-4 interaction from multi-energy scattering data

open access: yes, 1998
We present the first successful potential model description of Li-6 -- He-4 scattering. The differential cross-sections for three energies and the vector analyzing powers for two energies were fitted by a single potential with energy dependent imaginary ...
Bingham   +26 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The continuum discretized coupled-channels method and its applications

open access: yes, 2012
This is a review on recent developments of the continuum discretized coupled-channels method (CDCC) and its applications to nuclear physics, cosmology and astrophysics, and nuclear engineering.
Matsumoto, Takuma   +3 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

折叠变体飞行器风洞试验模型设计与可靠性分析

open access: yesJixie chuandong, 2009
The special high-speed wind tunnel test model is a difficult problem in the aviation field. Aiming at the movement performance index of one morphing aircraft for high-speed wind tunnel,the controllable-folding morphing test model is designed.
李强, 李周复, 刘铁中
doaj  

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