Results 31 to 40 of about 391,837 (318)

Spectral characteristics of the mutant form GGBP/H152C of D-glucose/D-galactose-binding protein labeled with fluorescent dye BADAN: influence of external factors [PDF]

PeerJ, 2014
The mutant form GGBP/H152C of the D-glucose/D-galactose-binding protein with the solvatochromic dye BADAN linked to cysteine residue Cys 152 can be used as a potential base for a sensitive element of glucose biosensor system.
Alexander V. Fonin, Olga V. Stepanenko, Olga I. Povarova, Catherine A. Volova, Elizaveta M. Philippova, Grigory S. Bublikov, Irina M. Kuznetsova, Alexander P. Demchenko, Konstantin K. Turoverov   +8 more
doaj   +2 more sources

Protein Folding and Macromolecular Dynamics: Fundamental Limits of Length and Time Scales [PDF]

, 2012
In this thesis, physics-based models of protein folding at the secondary and tertiary level are developed to resolve long-standing issues of protein folding kinetics.
Lin, Milo Miaoyu
core   +1 more source

Folding-Assisted Peptide Disulfide Formation and Dimerization

, 2023
Disulfide bonds form covalent bonds between distal regions of peptides and proteins to dramatically impact their folding, stability, and oligomerization.
Clara G. Victorio (16475762), Nicholas Sawyer, Clara G. Victorio, Nicholas Sawyer (1344129)   +3 more
core   +1 more source

Protein GB1 folding and assembly from structural elements. [PDF]

, 2009
Folding of the Protein G B1 domain (PGB1) shifts with increasing salt concentration from a cooperative assembly of inherently unstructured subdomains to an assembly of partly pre-folded structures.
Xue, Wei-Feng, Bauer, Mikael C., Mikael C. Bauer, Bauer, Mikael, Wei-Feng Xue, Sara Linse, Linse, Sara   +6 more
core   +1 more source

Mimosine functionalized gold nanoparticles (Mimo-AuNPs) suppress β-amyloid aggregation and neuronal toxicity

Bioactive Materials, 2021
Evidence suggests that increased level/aggregation of beta-amyloid (Aβ) peptides initiate neurodegeneration and subsequent development of Alzheimer's disease (AD). At present, there is no effective treatment for AD. In this study, we reported the effects
Bibin G. Anand, Qi Wu, Govindarajan Karthivashan, Kiran P. Shejale, Sara Amidian, Holger Wille, Satyabrata Kar   +6 more
doaj   +1 more source

Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie

Frontiers in Neuroscience, 2015
Organotypic cerebellar slices represent a suitable model for characterizing and manipulating prion replication in complex cell environments. Organotypic slices recapitulate prion pathology and are amenable to drug testing in the absence of a blood-brain ...
Hanna eWolf, Andre eHossinger, Andrea eFehlinger, Sven eBuettner, Valerie eSim, Debbie eMcKenzie, Ina Maja Vorberg, Ina Maja Vorberg   +7 more
doaj   +1 more source

Joyce in the Fold, the Fold in Joyce

Novel, 2021
Following Gilles Deleuze's model of the baroque, this paper examines the figure of “the fold” as an aesthetic category relevant to modern art and literature. In particular, it proposes the fold as a means of reading Finnegans Wake. Joyce's work is read as an attempt to capture the being of language prior to its unfolding and codification in the ...
openaire   +1 more source

Photophysical Properties of Fluorescent Probe Thioflavin T in Crowded Milieu

Journal of Spectroscopy, 2017
Thioflavin T (ThT) is a widely used fluorescent probe of amyloid fibrils, which accompanies many serious neurodegenerative and other diseases. Until recently, examinations of processes of amyloid fibril formation in vitro were conducted in solutions ...
Natalia P. Rodina, Maksim I. Sulatsky, Anna I. Sulatskaya, Irina M. Kuznetsova, Vladimir N. Uversky, Konstantin K. Turoverov   +5 more
doaj   +1 more source

Into the fold [PDF]

Nature Methods, 2011
In spite of its promise, nanotechnology has seen little uptake among biologists. DNA origami may be able to avoid this fate.
openaire   +2 more sources

Microbial Composition, Disease Trajectory and Genetic Background in a Slow Onset Model of Frontotemporal Lobar Degeneration

Biomolecules
Slow-onset neurodegenerative disease in a low-expresser 2N4R P301L transgenic (Tg) mouse model is marked by neuroinflammation and by differing patterns of CNS deposition and accumulation of tau conformers, with such heterogeneities present even within ...
Nathalie Daude, Ivana Machado, Luis Arce, Jing Yang, David Westaway   +4 more
doaj   +1 more source