Results 161 to 170 of about 5,838 (218)
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Treatment of Psoriasis with Folic Acid Antagonists
Archives of Dermatology, 1958Since the reporting of clinical improvement observed in the treatment of psoriasis with aminopterin, 1 our interest has been aroused to reevaluate the results obtained with this drug as well as with its close relative amethopterin. These drugs were used in our private practice in relatively low but therapeutic dosage.
W F, EDMUNDSON, W B, GUY
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Folic Acid, its Analogs and Antagonists
1960Publisher Summary Folic acid has many functions in the body, and when it is lacking, anemia is only part of a generalized disorder that undermines the health of the sufferer. After a brief historical review, this chapter deals with the metabolic functions of folic acid. The actions of folic acid antagonists are considered and attention is directed to
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Risk of Fetal Exposure to Folic Acid Antagonists
Journal of Obstetrics and Gynaecology Canada, 2004Several folic acid antagonists are considered by the Food and Drug Administration (FDA) to be toxic or potentially toxic to fetuses, including some folic acid antagonists that were once considered safe, such as trimethoprim. Information on fetal exposure to folic acid antagonists is sparse.In this study, we conducted a thorough search of English ...
Shi Wu, Wen, Mark, Walker
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Reproductive Toxicology, 2005
Since the protective effect of folic acid (FA) on birth defects is well known, it is reasonable to assume intrauterine exposure to FA antagonists increases the risk on these defects. We have therefore performed case-control analyses to investigate the risk of intrauterine exposure to FA antagonists, using data on births from the EUROCAT Northern ...
Meijer, W.M. +3 more
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Since the protective effect of folic acid (FA) on birth defects is well known, it is reasonable to assume intrauterine exposure to FA antagonists increases the risk on these defects. We have therefore performed case-control analyses to investigate the risk of intrauterine exposure to FA antagonists, using data on births from the EUROCAT Northern ...
Meijer, W.M. +3 more
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FOLIC ACID ANTAGONISTS IN CANCER CHEMOTHERAPY
Pharmacological Reviews, 1962L, DELMONTE, T H, JUKES
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Rational Design of Folic Acid Antagonists
1974Although the title of this chapter implies that there has been a successful rational approach to the design of folic acid antagonists, a review of the history of these agents suggests quite the opposite. In more recent years the light of rationalism has begun to gleam more strongly and there promises to be an “age of reason” in the design of ...
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Folic acid Antagonists and Chromosomal Abnormalities.
British Journal of Dermatology, 1965T J, RYAN, M M, BODDINGTON, A I, SPRIGGS
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