Results 91 to 100 of about 19,954 (207)

Functional role of AKT signaling in bovine early embryonic development: potential link to embryotrophic actions of follistatin

Reproductive Biology and Endocrinology, 2018
Background TGF-β signaling pathways regulate several crucial processes in female reproduction. AKT is a non-SMAD signaling pathway regulated by TGF-β ligands essential for oocyte maturation and early embryonic development in the mouse, but its regulatory
Mohamed Ashry, Sandeep K. Rajput, Joseph K. Folger, Jason G. Knott, Nabil A. Hemeida, Omaima M. Kandil, Refaat S. Ragab, George W. Smith   +7 more
doaj   +1 more source

Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury [PDF]

, 2018
学位記番号 ...
Takahashi, Shunsuke, タカハシ, シュンスケ, 高橋, 駿介   +2 more
core  

Structure of the disulfide‐rich modules of a striking tandem repeat protein, avian cysteine‐rich eggshell membrane protein

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Avian eggshell membrane (ESM) is fabricated within the isthmus region of the oviduct and is comprised of three juxtaposed, predominantly proteinaceous layers lying between egg white and the calcified shell. The limiting membrane is less than 0.5 μm in thickness and forms the osmotic barrier for the egg. This first layer provides the foundation
Somayeh Zeinalilathori, Ryan W. Russell, Jean L. Ross, Shannon Modla, Jeffrey L. Caplan, Tatyana Polenova, Colin Thorpe   +6 more
wiley   +1 more source

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma [PDF]

, 2016
Activin A (ActA)/follistatin (FST) signaling has been shown to be deregulated in different tumor types including lung adenocarcinoma (LADC). Here, we report that serum ActA protein levels are significantly elevated in LADC patients (n=64) as compared ...
Alzheimer, Andl, Beer, Beer, Blackhall, Bracke, Brusselle, Cho, Coletta, Coletta, Coletta, Cui, Diamandis, Diamandis, Dome, Domont, Garay, Goodglick, Harrison, Hedger, Hill, Johansen, Kaplan, Kern, Kouroumalis, Leto, Leto, Li, Ling, Massague, Miao, Miyamoto, Mori, O'Hehir, Patz, Pauwels, Petraglia, Petzelbauer, Plomgaard, Regnard, Rimokh, Rini, Roncalli, Schneyer, Schulte-Hermann, Shainkin-Kestenbaum, Skarin, Sone, Stieber, Taguchi, Ueno, Vale, Viladiu, Woodruff, Wu, Xu, Yamamoto, Zhang, Zhang   +58 more
core   +1 more source

A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling [PDF]

, 2019
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, lethal malignancy that invades adjacent vasculatures and spreads to distant sites before clinical detection.
Alimperti, Styliani, Chen, Christopher S., Eyckmans, Jeroen, Lee, Esak, Lee, Jake June-Koo, Nguyen, Duc-Huy T., Norgard, Robert J., Stanger, Ben Z., Wong, Alec   +8 more
core   +1 more source

Following up on follistatin [PDF]

Science-Business eXchange, 2009
Ohio State University and Nationwide Children's Hospital researchers have advanced their work on follistatin gene therapy to show that it increased muscle mass and improved muscle strength in macaques. They hope to move into clinical trials to treat musculoskeletal diseases by mid-2010.
openaire   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 11-23, January 2026.
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

Follistatin [PDF]

, 2020
Annamaria Colao, Claudia Pivonello
openaire   +2 more sources

Low follistatin level is a causal risk factor for spontaneous abortion: a two-sample mendelian randomization study

Frontiers in Endocrinology
BackgroundRecurrent pregnancy loss is a distressing event during pregnancy, and understanding its causal factors is crucial. Follistatin, a glycoprotein involved in folliculogenesis and embryogenesis, has been implicated as a potential contributor to the
Chen Gong, Chen Gong, Chen Gong, Chen Gong, Wenzhi Yang, Xue Liu, Xinliang Li, Yutong Wang, Yutong Wang, Yutong Wang, Yutong Wang, Chan Tian, Chan Tian, Chan Tian, Chan Tian, Chan Tian   +15 more
doaj   +1 more source

Activin/follistatin system in grass carp pituitary cells: - Regulation by local release of growth hormone and luteinizing hormone and its functional role in growth hormone synthesis and secretion.

PLoS ONE, 2017
Gonadotrophin regulation by activin/follistatin system is well-documented, but the corresponding effect on growth hormone (GH) has not been fully characterized and with little information available in lower vertebrates, especially in fish models.
Roger S K Fung, Jin Bai, Karen W Y Yuen, Anderson O L Wong   +3 more
doaj   +1 more source