Results 91 to 100 of about 19,656 (205)
Frontiers in EndocrinologyBackgroundRecurrent pregnancy loss is a distressing event during pregnancy, and understanding its causal factors is crucial. Follistatin, a glycoprotein involved in folliculogenesis and embryogenesis, has been implicated as a potential contributor to the
Chen Gong +15 more
doaj +1 more source
Physiological Fluid Flow Moderates Fibroblast Responses to TGF-β1. [PDF]
, 2016 Fibroblasts are the major cellular component of connective tissue and experience mechanical perturbations due to matrix remodelling and interstitial fluid movement.
Ahluwalia +30 more
core +1 more source
Assessing Aβ‐independent effects of Module 42 on immune function in vitro
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION A deep multi‐omic analysis of post mortem human brains has identified a new co‐expression protein network – Module 42 (M42), strongly corelated with Alzheimer's disease (AD) pathology. M42 comprises 32 transmembrane and extracellular matrix (ECM)‐associated proteins, including the amyloid precursor protein (APP) and apolipoprotein
Ishita Ajith +7 more
wiley +1 more source
PLoS ONE, 2017 Gonadotrophin regulation by activin/follistatin system is well-documented, but the corresponding effect on growth hormone (GH) has not been fully characterized and with little information available in lower vertebrates, especially in fish models.
Roger S K Fung +3 more
doaj +1 more source
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. [PDF]
, 2017 Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed.
Amatucci, Aldo +16 more
core +2 more sources
Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała +3 more
wiley +1 more source
Following up on follistatin [PDF]
Science-Business eXchange, 2009 Ohio State University and Nationwide Children's Hospital researchers have advanced their work on follistatin gene therapy to show that it increased muscle mass and improved muscle strength in macaques. They hope to move into clinical trials to treat musculoskeletal diseases by mid-2010.
openaire +1 more source
Prediabetes Associates With Musculoskeletal Alterations Independent of Total Body Adiposity
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Excess adiposity is a major risk factor for insulin resistance, prediabetes, and Type 2 diabetes and increases the risk for sarcopenia and osteosarcopenia later in life. It has been proposed that altered metabolic function and musculoskeletal status in people with obesity are directly linked, presumably because they share common ...
Alan Fappi +10 more
wiley +1 more source
eLife, 2019 The mammalian auditory sensory epithelium has one of the most stereotyped cellular patterns known in vertebrates. Mechano-sensory hair cells are arranged in precise rows, with one row of inner and three rows of outer hair cells spanning the length of the
Meenakshi Prajapati-DiNubila +4 more
doaj +1 more source