Rationale and design of "Can Very Low Dose Rivaroxaban (VLDR) in addition to dual antiplatelet therapy improve thrombotic status in acute coronary syndrome (VaLiDate-R)" study : A randomised trial modulating endogenous fibrinolysis in patients with acute coronary syndrome [PDF]
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
Gorog, Diana A +5 more
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FONDAPARINUX IN THE TREATMENT OF ACUTE CORONARY SYNDROME
Fondaparinux is a parenteral selective factor-Xa inhibitor. The drug is successfully used in the treatment of acute coronary syndrome, and is characterized by the ideal profile of effectiveness and safety. In the case of ACS without ST-segment elevation,
O. O. Shakhmatova
doaj +1 more source
Economic analyses of venous thromboembolism prevention strategies in hospitalized patients: a systematic review [PDF]
INTRODUCTION: Despite evidence-based guidelines for venous thromboembolism prevention, substantial variability is found in practice. Many economic evaluations of new drugs for thromboembolism prevention do not occur prospectively with efficacy studies ...
Deborah J Cook +4 more
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Cerebral Venous Thrombosis:Current Status and Challenges
Our review introduces treatment strategies for short‐term, long‐term, and permanent CVT risk factors, focusing on anticoagulant selection and treatment duration. We also discuss the current status of endovascular therapy for CVT, noting that it remains a challenge due to limited evidence, and more research is needed to optimize this approach.
Wenbo Zuo +5 more
wiley +1 more source
Thromboembolism After Intramedullary Nailing for Metastatic Bone Lesions. [PDF]
BACKGROUND: The risk of venous thromboembolism (VTE) in patients undergoing intramedullary nailing for skeletal metastatic disease is currently undefined.
Abraham, John A +8 more
core +2 more sources
Fondaparinux is commonly used for treatment of heparin‐induced thrombocytopenia (HIT) despite lack of approval for this indication. High quality randomized controlled trials of this agent are unlikely to be forthcoming.
L. Linkins, George Hu, T. Warkentin
semanticscholar +1 more source
ABSTRACT Vaccine‐induced thrombotic thrombocytopenia (VITT) has been linked to vector‐based vaccines, but only four cases following whole‐virus vaccines (Sinopharm) have been reported, as far as we are aware. This systematic review aimed to compile the clinical and laboratory results of VITT development after Sinopharm vaccination.
Shafi Rehman +5 more
wiley +1 more source
The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard
The enzyme heparanase, an endo-β-glucuronidase, degrades heparan sulfate (HS) chains on the cell surface and in the extracellular matrix. Heparanase regulates numerous biological processes that drive tumour growth, metastasis and angiogenesis.
Mohit Chhabra, Vito Ferro
doaj +1 more source
Antiagregación y anticoagulación en síndromes coronarios agudos: niveles de evidencia [PDF]
Management of acute coronary syndromes (ACS) has moved rapidly in parallel with our understanding of the pathophysiological basis of the disease. In the eighties, the demonstration of the pivotal role of coronary thrombosis in the etiology of a ACS led ...
Garcia, R. (R.) +3 more
core
Anticoagulation therapy and proximal femoral fracture treatment: An update [PDF]
Hip fractures in the elderly population have become a ‘disease’ with increasing incidence. Most of the geriatric patients are affected by a number of comorbidities.
Giannoudis, PV +2 more
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