Results 71 to 80 of about 26,226 (199)
AEG‐AESPANC‐OPGE‐SIED‐SPG Ibero‐Latin American Guidelines on Acute Pancreatitis (iLATAM‐AP)
United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Karina Cárdenas‐Jaén +44 more
wiley +1 more source
Journal of the American Geriatrics Society, Volume 74, Issue 6, Page 1841-1844, June 2026.Cannabis use in older adults may have a broad range of effects in older adults impacting Mind, Mobility, Medications, Multi‐complexity, and what Matters Most.
Erik Fraunberger, Maia von Maltzahn
wiley +1 more source
Chemokine Oligomers and the Impact of Fondaparinux Binding [PDF]
Heparin, a widely used clinical anticoagulant, is generally well-tolerated; however, approximately 1% of patients develop heparin-induced thrombocytopenia (HIT), a serious side effect. While efforts to understand the role of chemokines in HIT development
Szekeres, Gergo Peter +3 more
core +2 more sources
FONDAPARINUX IN THE TREATMENT OF ACUTE CORONARY SYNDROME
Атеротромбоз, 2017 Fondaparinux is a parenteral selective factor-Xa inhibitor. The drug is successfully used in the treatment of acute coronary syndrome, and is characterized by the ideal profile of effectiveness and safety. In the case of ACS without ST-segment elevation,
O. O. Shakhmatova
doaj +1 more source
, 2006 David BergqvistDepartment of Surgery, University Hospital, Uppsala, SwedenAbstract: The antithrombin binding sequence of heparin, a pentasaccharide, has been synthesized as fondaparinux, an indirect, selective, and reversible factor Xa inhibitor.
David Bergqvist
core
The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard
Molecules, 2018 The enzyme heparanase, an endo-β-glucuronidase, degrades heparan sulfate (HS) chains on the cell surface and in the extracellular matrix. Heparanase regulates numerous biological processes that drive tumour growth, metastasis and angiogenesis.
Mohit Chhabra, Vito Ferro
doaj +1 more source
Produktprofil von Pentasaccharid (Fondaparinux-Natrium)
, 2001 ZusammenfassungMit dem Pentasaccharid (INN: Fondaparinux) wird demnächst der erste Vertreter einer neuen Substanzklasse von selektiven Faktor-Xa-Inhibitoren zur Verfügung stehen.
R. M. Bauersachs
core +1 more source
Arquivos Brasileiros de Cardiologia, 2012 FUNDAMENTO: O uso combinado de agentes antitrombínicos, antiplaquetários e estratégias invasivas na síndrome coronariana aguda sem supradesnivelamento do ST (SCAsSST) reduz eventos cardiovasculares. O fondaparinux demonstrou equivalência à enoxaparina na
Camila Pepe +3 more
doaj
Development of an oral form of fondaparinux
, 2012 Le fondaparinux (Arixtra®), anticoagulant de la classe des pentasaccharides de synthèse, est le premier inhibiteur d'origine synthétique, spécifique et indirect du facteur Xa de la coagulation.
Ralay-Ranaivo, Bettina
core
2-Naphthylmethyl Protecting Group Strategy for Streamlined Synthesis of a Fondaparinux Analogue
Fondaparinux synthesis remains challenging because of demanding stereochemical control, protecting group manipulation, and purification of highly functionalized intermediates.
Xiao Liu +10 more
core +1 more source