Results 81 to 90 of about 24,646 (191)

Chemokine Oligomers and the Impact of Fondaparinux Binding [PDF]

open access: yes
Heparin, a widely used clinical anticoagulant, is generally well-tolerated; however, approximately 1% of patients develop heparin-induced thrombocytopenia (HIT), a serious side effect. While efforts to understand the role of chemokines in HIT development
Szekeres, Gergo Peter   +3 more
core   +2 more sources

FONDAPARINUX IN THE TREATMENT OF ACUTE CORONARY SYNDROME

open access: yesАтеротромбоз, 2017
Fondaparinux is a parenteral selective factor-Xa inhibitor. The drug is successfully used in the treatment of acute coronary syndrome, and is characterized by the ideal profile of effectiveness and safety. In the case of ACS without ST-segment elevation,
O. O. Shakhmatova
doaj   +1 more source

Développement d’une forme orale du fondaparinux

open access: yes, 2012
Since its introduction in the market in 2002, fondaparinux (Arixtra®) is a drug of choice in the anticoagulant therapy. Its structure corresponds to the heparin pentasaccharide sequence that mediates its interaction with the natural plasma inhibitor of ...
Ralay-Ranaivo, Bettina
core   +1 more source

The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard

open access: yesMolecules, 2018
The enzyme heparanase, an endo-β-glucuronidase, degrades heparan sulfate (HS) chains on the cell surface and in the extracellular matrix. Heparanase regulates numerous biological processes that drive tumour growth, metastasis and angiogenesis.
Mohit Chhabra, Vito Ferro
doaj   +1 more source

Review of fondaparinux sodium injection for the prevention of venous thromboembolism in patients undergoing surgery

open access: yes, 2006
David BergqvistDepartment of Surgery, University Hospital, Uppsala, SwedenAbstract: The antithrombin binding sequence of heparin, a pentasaccharide, has been synthesized as fondaparinux, an indirect, selective, and reversible factor Xa inhibitor.
David Bergqvist
core  

Resiko Efek Samping Perdarahan pada Penggunaan Fondaparinux (Arixtra) sebagai Antikoagulan: Kajian Literatur

open access: yes, 2021
Perdarahan merupakan salah satu efek samping yang terjadi pada pasien yang menggunakan Antikoagulan.  Artikel ini menyajikan beberapa bukti terkait efek samping perdarahan akibat penggunaan Fondaparinux sebagai Antikoagulan. Fondaparinux adalah obat
Wicaksono, Anggoro   +1 more
core   +1 more source

Fondaparinux in the initial and long-term treatment of venous thromboembolism

open access: yes, 2015
BACKGROUND: Even in the absence of evidence on its long-term efficacy and safety, a number of patients with venous thromboembolism (VTE) receive long-term therapy with fondaparinux alone in everyday practice.
Pagán, B.   +142 more
core   +3 more sources

FONDAPARINUX USAGE IN NON-ST-ELEVATION ACUTE CORONARY SYNDROME

open access: yesРоссийский кардиологический журнал, 2015
Anticoagulation treatment is a vital component of acute coronary syndrome treatment. Selection of the most efficient and safe drug for the acute coronary syndrome patients without ST elevation (NSTEACS) depends on the strategy of treatment and is in fact
G. V. Mardaryan, S. A. Abugov
doaj   +1 more source

The use of fondaparinux for the treatment of venous thromboembolism in a patient with heparin-induced thombocytopenia and thrombosis caused by heparin flushes

open access: yes, 2008
Alex C Spyropoulos1, Sharyl Magnuson1, Sei Keng Koh21Clinical Thrombosis Center, Lovelace Medical Center, Albuquerque, NM, USA; 2Department of Pharmacy, Singapore General Hospital, SingaporeAbstract: Heparin-induced thrombocytopenia (HIT) is an ...
Sharyl Magnuson   +2 more
core  

Custo-efetividade de fondaparinux em pacientes com Síndrome Coronariana Aguda sem supradesnivelamento do ST

open access: yesArquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: O uso combinado de agentes antitrombínicos, antiplaquetários e estratégias invasivas na síndrome coronariana aguda sem supradesnivelamento do ST (SCAsSST) reduz eventos cardiovasculares. O fondaparinux demonstrou equivalência à enoxaparina na
Camila Pepe   +3 more
doaj  

Home - About - Disclaimer - Privacy