Results 61 to 70 of about 24,646 (191)

Application, tolerance and safety of fondaparinux therapy in a German hospital: a prospective single-centre experience.

, 2012
INTRODUCTION The pentasaccharide fondaparinux is widely approved for prophylaxis and treatment of thromboembolic diseases and therapy of acute coronary syndrome. It is also used off-label in patients with acute, suspected or antecedent heparin-induced
Schindewolf, Marc, Marc Schindewolf, Hartmut Kroll, Marzi, Ingo, Julia Scheuermann, Boehncke, Wolf-Henning, Roland Kaufmann, Ludwig, Ralf J, Ludwig, Ralf J., Kroll, Hartmut, Wolf-Henning Boehncke, Ingo Marzi, Scheuermann, Julia, Edelgard Lindhoff-Last, Ralf J. Ludwig, Kaufmann, Roland, Lindhoff-Last, Edelgard   +16 more
core   +1 more source

Beyond the Thrombus: Imaging‐Guided Management of Acute Coronary Syndrome

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Imaging‐guided management of acute coronary syndrome. ABSTRACT Intracoronary imaging is a true game‐changer in acute coronary syndromes, enhancing diagnostic accuracy while ensuring precise, mechanism‐driven, and patient‐tailored management.
Guillaume Guebey, Mathieu Chong, Adelin Barrier, Sarah Mauler‐Wittwer, Stéphane Noble, Quentin Liabot   +5 more
wiley   +1 more source

EARLY DISCONTINUATION OF FONDAPARINUX IN LOW-RISK PATIENTS HOSPITALIZED WITH NON-ST-ELEVATION ACUTE CORONARY SYNDROME: MARKERS OF HEMOSTASIS ACTIVATION AND IN-HOSPITAL OUTCOMES

Российский кардиологический журнал, 2015
Current guidelines recommend use of anticoagulants (preferably fondaparinux) until hospital discharge in non-invasively treated patients (pts) with non-ST-segment elevation acute coronary syndrome (NSTEACS).
I. S. Yavelov, A. S. Knyazev, A. B. Dobrovolsky, N. A. Gratsiansky   +3 more
doaj   +1 more source

Fitusiran treatment modulates the ratio between alpha‐ and beta‐antithrombin isoforms

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Antithrombin (AT) circulates as two distinct isoforms, alpha‐ and beta‐AT, which differ in their glycosylation profiles; alpha‐AT is fully glycosylated at positions Asn128, Asn167, Asn187, and Asn224, whereas beta‐AT lacks Asn167 glycosylation.
Geneviève McCluskey, Hortense Maynadié, Delphine Borgel, Laurent Frenzel, Annie Harroche, Elsa Bianchini, Stephanie Roullet, Olivier D. Christophe, Cecile V. Denis, Caterina Casari, Peter J. Lenting   +10 more
wiley   +1 more source

Fucoidan: An Update on Function, Role in Human Health and Applications

Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
Fucoidan is a promising bioactive compound with anti‐inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, thanks to its epigenetic potential, ability to modulate autophagic mechanisms and possibility adjuvant agent or bioactive component of the drug delivery systems, fucoidan is a promising ...
Sharon Critelli, Marilena Celano
wiley   +1 more source

Fully Synthetic Non‐Carbohydrate Heparin Mimetics—Perspectives for Therapeutic Anticoagulation and Beyond?

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
Fully synthetic sulfated non‐carbohydrate polymers for structurally mimicking the polysaccharide glycosaminoglycan heparin in its anticoagulant activities with further prospects to pleiotropic effects in oncology and in antiviral approaches. ABSTRACT Heparin is one of the oldest drugs on the market.
Katrin Nekipelov, Vito Ferro, Gerd Bendas   +2 more
wiley   +1 more source

Unlocking the potential of fondaparinux: guideline for optimal usage and clinical suggestions (2023)

Frontiers in Pharmacology
Background: Thromboembolic disease is associated with a high rate of disability or death and gravely jeopardizes people’s health and places considerable financial pressure on society.
Qinan Yin, Qinan Yin, Lizhu Han, Lizhu Han, Yin Wang, Fengjiao Kang, Fengqun Cai, Liuyun Wu, Xingyue Zheng, Lian Li, Li e Dong, Limei Dong, Shuhong Liang, Min Chen, Min Chen, Yong Yang, Yong Yang, Yuan Bian, Yuan Bian   +18 more
doaj   +1 more source

Clinical experience with fondaparinux in antiaggregate patients undergoing total hip and knee arthroplasty

Italian Journal of Medicine, 2013
Patients undergoing total hip arthroplasty or total knee arthroplasty have a high risk for post-operative venous thromboembolism. The current study addressed the use of fondaparinux post-operatively in 556 patients with antiplatelet therapy in order to ...
Guido Grappiolo, Marco Scardino, Giuseppe Mazziotta, Stefano Quaini, Corrado Lodigiani, Matteo Carlo Ferrari   +5 more
doaj   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 259-271, April 2026.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Clinical Profile and Admission Outcomes of Patients With Acute Pulmonary Embolism at a Resource‐Constrained Hospital in Ghana: A Retrospective Pilot Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Pulmonary embolism is a cardiovascular disease associated with significant morbidity and mortality. There is a paucity of literature regarding this condition from the Ghanaian perspective. This study aimed at evaluating the clinical profile and admission outcomes of patients with acute pulmonary embolism at the Methodist ...
Prosper Adjei, Samuel Kyeremeh Adjei, Kingsley Owusu Manu   +2 more
wiley   +1 more source