Results 61 to 70 of about 4,249 (125)

Mortality Outcomes of Combined Heart and Liver Transplantation and Isolated Heart Transplantation Following Fontan Procedures: A Systematic Review and Meta‐Analysis

Pediatric Transplantation, Volume 29, Issue 7, November 2025.
This meta‐analysis compares mortality rates in Fontan patients undergoing combined heart–liver transplantation (CHLT) versus isolated heart transplantation (HT), showing comparable mortality and reinforcing the importance of comprehensive liver evaluation in transplant candidates.
Oscar Holmvard, Mariana Póvoa‐Corrêa, Adriana Macintyre Innocenzi, Lucio Filgueiras Pacheco, Daniella Braz Parente, Ronir Raggio Luiz, Jessica Pronestino de Lima Moreira, Renata de Mello Perez, Fernanda Padrão Fernandes, Renata Moll‐Bernardes   +9 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, Volume 599, Issue 20, Page 2954-2972, October 2025.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Gut Dysbiosis in Patients With Fontan Circulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The process underlying Fontan pathophysiology is multifactorial and may include gut dysbiosis (GD). We investigated the presence of GD and elucidated its correlation with Fontan pathophysiology.
Hideo Ohuchi, Ryotaro Asano, Aki Mori, Tomohiko Ishibashi, Daisuke Motooka, Michikazu Nakai, Yoshikazu Nakaoka   +6 more
doaj   +1 more source

Alterations in Liver Perfusion in Adults With Fontan Circulation as Assessed by Dual Cholate Clearance

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Fontan circulation (FC) in complex congenital heart disease is characterized by altered hemodynamics and associated with Fontan‐associated liver disease. Patients with FC may exhibit abnormalities in cholate clearance due to abnormal perfusion.
Yuli Y. Kim, Annique Nyman, Yuan‐Shung Huang, Alexis Z. Tomlinson, Michael P. McRae, Greg T. Everson, Sumeet Vaikunth, Benjamin Rosenthal, Jack Rychik, Maarouf A. Hoteit   +9 more
doaj   +1 more source

Abstracts From PVRI 2026 Dublin

Pulmonary Circulation, Volume 16, Issue 2, June 2026.
wiley   +1 more source

Endothelin-1 in the failing Fontan: pathobiology, precision therapeutics, and future trial design

Frontiers in Pediatrics
The Fontan circulation, devised as definitive palliation for single-ventricle congenital heart disease, imposes systemic venous hypertension, loss of pulmonary arterial pulsatility, and restricted preload reserve.
Iman Maiza
doaj   +1 more source

Revisiting Hepatic Fibrosis Risk in Congenital Heart Disease: Insights from Non-Invasive Markers and Echocardiography

Children
Background/Objectives: This study aimed to investigate the prevalence of liver damage and its associated non-invasive markers and echocardiographic risk factors in patients who underwent surgery for congenital heart disease.
Fusako Yamazaki, Hiroteru Kamimura, Saori Endo, Suguru Miida, Hiroki Maruyama, Tomoaki Yoshida, Masaru Kumagai, Naruhiro Kimura, Hiroyuki Abe, Akira Sakamaki, Takeshi Yokoo, Masanori Tsukada, Fujito Numano, Akihiko Saitoh, Maya Watanabe, Shuichi Shiraishi, Masanori Tsuchida, Shinya Fujiki, Takeshi Kashimura, Takayuki Inomata, Hirofumi Nonaka, Kenya Kamimura, Atsunori Tsuchiya, Shuji Terai   +23 more
doaj   +1 more source

Association of Fontan Pathophysiology With Plasma Bile Acids

JACC: Advances
Background: Patients with Fontan circulation are frail and experience multisystem dysfunction including impaired exercise capacity, low resting and exercise-augmented cardiac output, and progressive liver fibrosis.
Ashish H. Shah, MD, MD-Research, Arun Surendran, MSc, Pedram Hassan-Tash, BSc, MD, C. Nolan Turnbull, BSc, Nicole Johnston, MSc, David Goodlett, BSc, PhD, Jun Han, PhD, Robin A. Ducas, MD, James W. Tam, MD, Eberhard Renner, MD, Todd A. Duhamel, PhD, Michel Aliani, MSc, PhD, Amir Ravandi, MD, PhD, Richard A. Krasuski, MD   +13 more
doaj   +1 more source

Fontan-associated liver disease. [PDF]

Clin Liver Dis (Hoboken), 2023
Hilscher MB, Kamath PS.
europepmc   +1 more source

Prognostic biomarkers in Fontan associated liver disease. [PDF]

Transl Pediatr
Anouti A, Aqul A, Bartlett JA, Nonga D, Danpanichkul P, Rady ED, Cotter TG, Hassan S, Pandurangi S.   +8 more
europepmc   +1 more source