Results 11 to 20 of about 4,299 (147)

Multiple Liver Nodules in Fontan-Associated Liver Disease [PDF]

GE: Portuguese Journal of Gastroenterology, 2023
Raquel R. Mendes, Luis Marques, Pedro C. Figueiredo   +2 more
doaj   +4 more sources

Efficacy of Magnetic Resonance Elastography in Fontan‐Associated Liver Disease [PDF]

JGH Open
Aims Many patients develop Fontan‐associated liver disease (FALD) after undergoing the Fontan procedure—a surgical treatment for congenital heart disease such as single ventricle—owing to changes in venous pressure and cardiac output. Liver biopsy is the
Michihiro Iwaki, Takashi Kobayashi, Naohiro Wada, Yumi Saiki, Koki Nagai, Asako Nogami, Shun Kawai, Shingo Koyama, Daisuke Utsunomiya, Atsushi Nakajima, Masato Yoneda   +10 more
doaj   +5 more sources

Non-invasive biomarkers of Fontan-associated liver disease [PDF]

JHEP Reports, 2021
Background & Aims: Fontan-associated liver disease (FALD) has emerged as an important morbidity following surgical palliation of single ventricle congenital heart disease. In this study, non-invasive biomarkers that may be associated with severity of
Juliet Emamaullee, Sara Khan, Carly Weaver, Cameron Goldbeck, George Yanni, Rohit Kohli, Yuri Genyk, Shengmei Zhou, Nick Shillingford, Patrick M. Sullivan, Cheryl Takao, Jon Detterich, Paul F. Kantor, John D. Cleveland, Cynthia Herrington, S. Ram Kumar, Vaughn Starnes, Sarah Badran, Neil D. Patel   +18 more
doaj   +3 more sources

Fontan-associated liver disease and hepatocellular carcinoma in adults [PDF]

Scientific Reports, 2020
The Fontan operation creates a unique circulation, and is a palliative therapy for patients with single-ventricle congenital heart disease. Increased venous pressure and decreased cardiac output and hepatic venous drainage result in sinusoidal dilatation
Tomomi Kogiso, Katsutoshi Tokushige
doaj   +3 more sources

Fontan-Associated Liver Disease. [PDF]

Semin Liver Dis
Fontan-associated liver disease (FALD) occurs in all patients who have undergone Fontan palliation for functional single ventricle congenital heart defects. While liver fibrosis is universal in patients who have undergone Fontan palliation, FALD may lead to more serious consequences including portal hypertension, cirrhosis, and hepatocellular carcinoma.
Hilscher MB, Johnson JN.
europepmc   +8 more sources

Fontan-associated liver disease: the importance of multidisciplinary teamwork in its management [PDF]

Frontiers in Medicine
The Fontan operation, which directly connects the superior and inferior vena cava to the pulmonary artery, is a palliative surgery for children with a functional or anatomic single ventricle.
Tomoya Tsuchihashi, Yuki Cho, Daisuke Tokuhara, Daisuke Tokuhara   +3 more
doaj   +2 more sources

Shear wave dispersion to assess liver disease progression in Fontan-associated liver disease.

PLoS ONE, 2022
AimWe aimed to analyze the dispersion slope (DS) using shear wave dispersion (SWD) in patients with Fontan-associated liver disease (FALD) and to investigate its utility as a biomarker of disease progression.MethodsThis cross-sectional study enrolled 27 ...
Tomoaki Nagasawa, Hidekatsu Kuroda, Tamami Abe, Hirofumi Saiki, Yasuhiro Takikawa   +4 more
doaj   +3 more sources

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan-Associated Liver Disease. [PDF]

Adv Sci (Weinh)
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Rezapourdamanab S, Amoli MS, Mukherjee T, Bagheri M, Hwang B, Jin L, Singh Y, Norton S, Bongirwar AV, Karnik S, Dasi LP, Avazmohammadi R, Romero R, Bauser-Heaton HD, Serpooshan V.   +14 more
europepmc   +2 more sources

Fontan-associated liver disease. [PDF]

Clin Liver Dis (Hoboken), 2023
Hilscher MB, Kamath PS.
europepmc   +3 more sources

A One-Dimensional (1D) Computational Fluid Dynamics Study of Fontan-Associated Liver Disease (FALD). [PDF]

Int J Numer Method Biomed Eng
Fontan‐associated liver disease (FALD) is a disorder arising from congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Through perfusion analysis, we find that as FALD progresses, there are increased pressures and decreased flow to certain regions of liver tissue.
Li Y, Weigand JD, Puelz C, Olufsen MS, Taylor-Lapole A.   +4 more
europepmc   +2 more sources