Results 101 to 110 of about 9,350,244 (365)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Food safety in food security and food trade: [PDF]

open access: yes
CONTENTS: Overview / Laurian J. Unnevehr; Food Safety as a Public Health Issue for Developing Countries / Fritz K. K ferstein; Mycotoxin Food Safety Risk in Developing Countries / Ramesh V.
Unnevehr, Laurian J., ed.
core  

The New Food Safety [PDF]

open access: yes, 2019
A safe food supply is essential for a healthy society. Our food system is replete with different types of risk, yet food safety is often narrowly understood as encompassing only foodborne illness and other risks related directly to food ingestion.
Broad Leib, Emily M., Pollans, Margot J.
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

The bromides of gods, the passions of humans

open access: yesNWIG, 1996
[First paragraph] Histoire du chocolat. NlKlTA HARWICH. Paris: Desjonquères, 1992. 292 pp. (Paper, n.p.) The Chocolate Tree: A Natural History of Cacao. ALLEN M. YOUNG. Washington DC: Smithsonian Institution Press, 1994. xv + 200 pp. (Cloth US$
Sidney W. Mintz
doaj  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Improving Food Security in Africa: Highlights of 25 Years of Research, Capacity-Building, and Outreach. [PDF]

open access: yes
Decades of research have led to substantially improved understanding of the nature of food insecurity. A combination of economic growth and targeted programs resulted in a steady fall (until the food crisis of 2007/08) in the percentage of the world’s ...
Food Security Group at Michigan State University
core   +1 more source

No. 03: Urban Food Deserts and Climate Change in African Cities [PDF]

open access: yes, 2016
The underlying assumption in much of the Euro-American food deserts literature is that urban food deserts are dynamic spaces, expanding and contracting with the advent and withdrawal of supermarkets. This discussion paper argues that to tie such dynamism
Caesar, Mary, Crush, Jonathan
core   +1 more source

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