Results 111 to 120 of about 11,802,464 (361)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Installment 2 of "Creating a Sustainable Food Future": Reducing Food Loss and Waste [PDF]

open access: yes, 2013
Approximately one out of every four calories grown to feed people is not ultimately consumed by humans. Food is lost and wasted to a varying extent across the globe, across all stages of the food value chain, and across all types of food.
Brian Lipinski   +5 more
core  

Macroeconomic effects of disruptions in global food commodity markets [PDF]

open access: yes, 2016
We use two approaches to examine the macroeconomic consequences of disruptions in global food commodity markets. First, we embed a novel quarterly composite global production index for the four basic staples (corn, wheat, rice and soybeans) in a standard
De Winne, Jasmien, Peersman, Gert
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Food for Thought about Environmental Values and Food Demand [PDF]

open access: yes, 2008
It is a controversial discussion whether consumers are taking care of environmental issues when buying food. This question seems to be of significance to understand the demand for organic products, and thus many investigations have been made in this ...
Henseleit, Dr. Meike
core  

Food and welfare in India, c. 1900–1950 [PDF]

open access: yes, 2008
In 2001, the People's Union for Civil Liberties submitted a writ petition to the Supreme Court of India on the “right to food.” The petitioner was a voluntary human rights organization; the initial respondents were the Government of India, the Food ...
Adyanthaya   +61 more
core   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Association of dietary intake with a risk factor of atherosclerosis – abdominal obesity in men of Novosibirsk

open access: yesАтеросклероз, 2015
Aim. To evaluate association between the nutrition habits and abdominal obesity in cross-sectional population study among men 45-69 years in Novosibirsk. Materials and methods.
A. K. Kuntsevich   +5 more
doaj  

The Use of Medical Foods to Fight Chronic Diseases: A Narrative Review

open access: yesJournal of Agricultural Sciences
Chronic diseases cannot be treated completely, and, therefore, often require repeated treatments. This issue leads to long-term drug utilization. However, medical foods can offer alternative natural drugs in the management and treatment of chronic ...
Aslihan Demirdöven, Hilal Meral
doaj   +1 more source

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