Results 71 to 80 of about 4,019,080 (309)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Food Environment, Food Store Access, Consumer Behavior, and Diet [PDF]

open access: yes
Food Environment, Food Deserts, Obesity, Consumer Behavior, Diet, Food Consumption/Nutrition/Food Safety, I18, R50,
Ver Ploeg, Michele
core   +1 more source

Refugees, Food Insecurity, and Community Gardens [PDF]

open access: yes, 2011
Nearly nine in ten resettled refugee households endure food insecurity, meaning that they are without “access to sufficient, safe, nutritious food to maintain a healthy and active life.” Because western New York resettles hundreds of refugees per year ...
Rolston, Dorian
core   +1 more source

Wood mouse feeding effort and decision-making when encountering a restricted unknown food source [PDF]

open access: yes, 2019
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Barja, Isabel   +2 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A comparative analysis of alternative food security indicators, using farm workers in the Northern Cape Province as a case study [PDF]

open access: yes, 2019
Magister Artium (Development Studies) - MA(DVS)The concept of food insecurity is complex and difficult to measure. Food insecurity is measured at different levels – global, national, household and individual. In order to have appropriate assessments of
Devereux, Stephen, Ndondo, Zona
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Online grocery purchasing in Mississippi: associations with broadband, rurality, and household characteristics

open access: yesFrontiers in Nutrition
IntroductionThis study investigates the sociodemographic, economic, and area characteristics associated with Online Grocery Purchasing (OGP) use among adult residents of Mississippi.
Will Davis   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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