Results 61 to 70 of about 7,013,092 (301)

How did the COVID-19 pandemic affect food environment, food purchase, and fish consumption among low-income urban households in Bangladesh—A path analysis

Frontiers in Public Health, 2022
BackgroundAnimal source foods, especially fish is the most commonly consumed and an important source of macro and micronutrients in the diet of the urban low-income residents.
Mahsina Syeda Akter, Elise F. Talsma, Edith J. M. Feskens, Shakuntala H. Thilsted, Sabrina Rasheed   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Access to Rights and Access to Food - From Food Aid as a Lever for Access to Rights to the Recognition of Access to Food as a Right

, 2023
Si l’aide alimentaire est souvent présentée comme un « point d’entrée » ou un « levier » pour l’accès aux droits, ce sont les droits fondamentaux dans des domaines tels que le logement, la protection de la santé, l’emploi, protection sociale, etc. qui sont considérés.La protection du besoin essentiel de l’accès à l’alimentation, en tant que droit ...
openaire   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

SNAP at the Community Scale: How Neighborhood Characteristics Affect Participation and Food Access.

American Journal of Public Health, 2019
Cities are spatially diverse, with enclaves of particular demographic groups, clusters of businesses, and pockets of low-income individuals living amid affluence.This essay presents data from New York City to illustrate the importance of measuring and ...
N. Cohen
semanticscholar   +1 more source

Food Security among Rural Communities: Insights from Iran

World
“Zero Hunger”, the second Sustainable Development Goal, is one of humanity’s most critical challenges and is deeply interlinked with food security. Food security encompasses multiple levels, from food availability to access to food stability.
Ali Akbar Barati, Khalil Kalantari, Jassem Gholabifar, Milad Zhoolideh   +3 more
doaj   +1 more source