Results 81 to 90 of about 4,019,080 (309)

Examining the Effect of SES on Access to Nutritional Food [PDF]

, 2012
America has recently seen an increasing epidemic of diet related diseases in people of all backgrounds. However, the brunt of these health risks, especially those stemming from obesity, seem to disproportionately fall on those of lower socioeconomic ...
White, Rebecca
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Rural Food Insecurity: A Longitudinal Analysis of Low-Income Rural Households with Children in the South

RSF: The Russell Sage Foundation Journal of the Social Sciences, 2022
Researchers have noted large spatial variations in rates of food insecurity. But little research exists on why this is so and the impacts it has on rural families.
Sarah Bowen, Sinikka Elliott, Annie Hardison-Moody   +2 more
doaj   +1 more source

No. 09: The State of Household Food Security in Nanjing, China [PDF]

, 2018
This report on the state of food security in Nanjing, China, is based on a 2015 city-wide survey conducted by Nanjing University and the Hungry Cities Partnership.
Si, Zhenzhong, Zhong, Taiyang
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Closing the food access gap in rural Mississippi

Journal of Agriculture, Food Systems, and Community Development
Rural Mississippi faces severe health challenges, ranking lowest among all U.S. states in health out­comes and highest in diet-related chronic diseases.
Ivonne Quiroz, Katherine Fraser, Sara Evans Miller, Kevin Coogan, Nevin Cohen   +4 more
doaj  

Migration, Urbanization and Food Security in Cities of the Global South: 26–27 November 2012, Cape Town, South Africa [PDF]

, 2013
The disjuncture between food security, migration and urbanization must be overcome. It is an institutional as well as a thematic disconnect on a global scale. Food security is primarily about access to food, not agricultural production.
Crush, Jonathan
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Impact of agricultural land use changes on food access in Mwatate Sub-County, Taita Taveta County, Kenya

Frontiers in Sustainable Food Systems
IntroductionWhereas Sustainable Development Goal 2 seeks to achieve zero hunger by 2030, food security remains a global challenge. Therefore, SDG 2 aims to achieve sufficient food access through sustainable agriculture. This is in line with the tenets of
Obeka Mwanzi Bonventure, Elisabeth Wacker, Halimu Shauri, Walter Timo de Vries   +3 more
doaj   +1 more source