Results 221 to 230 of about 245,551 (329)

Taste Profile and Relative Bioavailability of Tovorafenib Powder for Oral Suspension and Food Effect of the Tovorafenib Tablet in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang   +6 more
wiley   +1 more source

Omalizumab in Food Allergy in Children: Current Evidence and Future Perspectives. [PDF]

open access: yesLife (Basel)
Indolfi C   +6 more
europepmc   +1 more source

Carrot allergy: Double-blinded, placebo-controlled food challenge and identification of allergens [PDF]

open access: bronze, 2001
Barbara Ballmer‐Weber   +5 more
openalex   +1 more source

Evaluation of CYP2C19 Clinical Decision Support Alerts to Guide P2Y12 Inhibitor Prescribing

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
P2Y12 inhibitor selection involves numerous factors, including CYP2C19 genetics, since evidence demonstrates reduced clopidogrel efficacy in patients with decreased or no function CYP2C19 variants. In 2020, Indiana University health embedded interruptive clinical decision support (CDS) alerts in the electronic health record (EHR) to recommend ...
Ashley N. Springer   +14 more
wiley   +1 more source

The Role of Omalizumab as an Adjunct to Oral Immunotherapy in Pediatric Food Allergy: A Systematic Review. [PDF]

open access: yesCureus
Khidir Mustafa AA   +6 more
europepmc   +1 more source

Predicting Maternal and Fetal Exposures of Elexacaftor–Tezacaftor–Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The use of elexacaftor/tezacaftor/ivacaftor (ETI) has been associated with increased fertility in women with cystic fibrosis (CF) and is increasingly used during pregnancy to support both maternal and fetal health. However, little is known about the pharmacokinetics (PK) of ETI during pregnancy, which is crucial for optimizing its efficacy and safety ...
Eunjin Hong   +8 more
wiley   +1 more source

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