Results 171 to 180 of about 315,996 (308)

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

The Healthiness of Packaged Food and Beverage Products in the Kingdom of Saudi Arabia. [PDF]

Nutrients
Dunford EK, Alsukait RF, Alkhalaf MM, Hamza MM, Shahin MA, Cetinkaya V, Alghaith T.   +6 more
europepmc   +1 more source

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

Clinical Pharmacology &Therapeutics, EarlyView.
Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo, Outi Lapatto‐Reiniluoto, Mika Kurkela, Mikko Neuvonen, Eeva Moilanen, Mikko Niemi, Aleksi Tornio, Janne T. Backman   +7 more
wiley   +1 more source

The nature and frequency of food and beverage marketing on Kenyan national television: a mixed-method analysis of food advertisements, parent and children's perspectives. [PDF]

BMC Med
Wanjohi MN, Karugu CH, Agyemang C, Holdsworth M, Laar A, Klipstein-Grobusch K, Ojiambo V, Mugo S, Kimani-Murage EW, Vandevijvere S, Asiki G.   +10 more
europepmc   +1 more source

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

Clinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo, Donna A. Volpe, Anik Chaturbedi, Aanchal Shah, Ashok Krishna, Paula L Hyland, Giri Vegesna, Cheng‐Hui Hsiao, Ryan De Palma, Melanie Fein, Rodney Rouse, Jeffry Florian   +11 more
wiley   +1 more source

Understanding Australian adults' preferences for setting goals to reduce unhealthy food and beverage intake: a cross-sectional study. [PDF]

J Nutr Sci
Mauch CE, Fuchs A, Howlett CA, Hendrie GA.   +3 more
europepmc   +1 more source

Patterns and Drivers of Spanish Corporate Commitment to the UN Global Compact: A Quantitative Approach

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This paper presents a quantitative assessment of Spanish companies' commitment to the United Nations Global Compact (UNGC) and the Sustainable Development Goals (SDGs). Analyzing over 1000 participating firms, we identify prioritization patterns and examine structural factors influencing SDG adherence.
Juan Laborda, Juan Pérez
wiley   +1 more source

Using artificial intelligence and computer vision to detect and monitor unhealthy child-directed food and beverage marketing: a data-driven study. [PDF]

EClinicalMedicine
Hu G, Gross O, Ziraldo E, Mulligan C, Soberman D, Dewan M, Lewis K, Nomani R, Lu A, L'Abbé MR.   +9 more
europepmc   +1 more source

Purpose and Profit: Social and Environmental Marketing for Large Companies in Adverse Scenarios

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This qualitative study explored how large companies use social and environmental marketing to boost results in adverse scenarios, analyzing interviews with marketing managers and public documents. The findings reveal distinct strategies. To attract investors, environmental, social, and governance (ESG) communication is targeted at limited ...
Celso Jacubavicius, Giancarlo Medeiros Pereira, Oduvaldo Vendrametto, Miriam Borchardt, Gabriel Sperandio Milan   +4 more
wiley   +1 more source

Development, validity and reliability of the street food and beverage tool. [PDF]

Public Health Nutr
López U, Aburto TC, González C, Barranco V, Chavira J, Hernandez-Barrera L, Olvera AG, Nieto C, Romero-Martínez M, Medina C, Barquera S.   +10 more
europepmc   +1 more source