Results 41 to 50 of about 93,351 (301)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Food Supply Chain Integration: Learning from the Supply Chain Superpower

open access: yesInternational Journal of Managing Value and Supply Chains, 2015
Supply chain integration is postulated as the key to achieve supply chain management excellence. There is an equivocal claim that Japanese companies are better at managing their supply chains. Yet, little is known about the Japanese food supply chain. Ten interviews with supply chain managers were conducted using an open ended interview approach. These
IntanMarzitaSaidon   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Environmental and Cost Impacts of Food Waste in University Canteen from a Life Cycle Perspective

open access: yesEnergies, 2021
Food waste has caused double waste of resources in the food itself and the food supply chain of production, transportation, cooking, and processing, resulting in unnecessary greenhouse gas emissions and economic losses.
Jing Li, Wei Li, Lei Wang, Baihui Jin
doaj   +1 more source

Integration of logistics network in local food supply chains [PDF]

open access: yes, 2013
The demand for locally produced food is increasing as global food supply system has considerably affected the confidence of consumers by increasing tonne-kilometres, food safety risk, environmental impact, and disconnecting local food producers and ...
Bosona, Techane
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Asset specificity, inter-firm ecosystem, firm adaptability and supply chain integration [PDF]

open access: yesModern Supply Chain Research and Applications
Purpose – This study investigates the effect of asset specificity, inter-firm ecosystem and firm adaptability on supply chain integration. The study also investigates the mediation effect of firm adaptability on the relationship between asset specificity
Farida Nakayima   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Pioneering food safety: Blockchain's integration in supply chain surveillance

open access: yesJournal of Agriculture and Food Research
Ensuring food safety in a world facing escalating demand and complex supply chains is a pressing challenge. Despite increasing awareness, obstacles such as information distribution, financial limitations, and insufficient infrastructure impede food ...
Keru Duan   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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