Results 61 to 70 of about 7,557,329 (298)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Impact of Supply chain integration on competitive capabilities in Food and Beverages Industries [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2012
This study examines the impact of supply chain integration (SCI)dimensions on competitive capabilities. For this purpose, therelationship between dimensions of SCI (internal integration andexternal integration including supplier integration and ...
Shamsodin Nazemi, Fatemeh Kharidar
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Supply chain collaboration and integration enhance the response of fast-moving consumer goods manufacturers and retailers to customer’s requirements

open access: yesSouth African Journal of Business Management, 2018
Supply chain management has a critical role in steering business success through coordinated activities of the value chain partners. The success of fast-moving consumer goods companies (FMCGs) has a direct relationship with the performance of the leading
Ken Mathu, Selepe Phetla
doaj   +1 more source

Methods for managing the food value chain [PDF]

open access: yesУправленец, 2019
The paper aims to develop the methods for managing the food value chain at the level of a region and business entities. Methodologically, the study rests on the concept of value chains that takes into account the interests of governing bodies and is ...
Zhanna A. Ermakova   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Supply Chain Integration: A Case-based Investigation of Status, Barriers, and Paths to Enhancement. [PDF]

open access: yes, 2009
In a global marketplace supply chain integration is recognised to be one of today's competitive advantages; where the aim is to optimise material- and information-flows inside the focal company and also across supply chain companies.
Boehme, Tillmann
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Integrated Food Chain Surveillance System for Salmonella spp. in Mexico1 [PDF]

open access: yesEmerging Infectious Diseases, 2008
Few developing countries have foodborne pathogen surveillance systems, and none of these integrates data from humans, food, and animals. We describe the implementation of a 4-state, integrated food chain surveillance system (IFCS) for Salmonella spp. in Mexico.
Mussaret B. Zaidi   +11 more
openaire   +3 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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