Results 41 to 50 of about 383,029 (253)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Studying The Classification And Quality Of Food

The American Journal of Agriculture and Biomedical Engineering, 2021
This article examines the analysis of the quality of food products in the world markets. The negative impact of low-quality goods on the health of the population and the economy of the country is substantiated, as well as issues of studying modern methods for determining the composition of low-quality goods.
Kurbonkul Mavlankulovich Karimkulov, Ikromjon Esanboyevich Uzohkov, Madraim Khasanovich Sarikulov   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Machine learning–assisted matrix-assisted laser desorption/ionization time-of-flight mass spectrometry toward rapid classification of milk products

Journal of Dairy Science
: This study established a method for rapid classification of milk products by combining MALDI-TOF MS analysis with machine learning techniques. The analysis of 2 different types of milk products was used as an example.
Yaju Zhao, Hang Yuan, Danke Xu, Zhengyong Zhang, Yinsheng Zhang, Haiyan Wang   +5 more
doaj   +1 more source

An Automated Image-Based Dietary Assessment System for Mediterranean Foods

IEEE Open Journal of Engineering in Medicine and Biology, 2023
Goal: The modern way of living has significantly influenced the daily diet. The ever-increasing number of people with obesity, diabetes and cardiovascular diseases stresses the need to find tools that could help in the daily intake of the necessary ...
Fotios S. Konstantakopoulos, Eleni I. Georga, Dimitrios I. Fotiadis   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Early bread mold detection through microscopic images using convolutional neural network

Current Research in Food Science, 2023
Mold on bread in the early stages of growth is difficult to discern with the naked eye. Visual inspection and expiration dates are imprecise approaches that consumers rely on to detect bread spoilage.
Panisa Treepong, Nawanol Theera-Ampornpunt   +1 more
doaj   +1 more source