Results 131 to 140 of about 26,092 (266)

Visualising backward information propagation in deep reinforcement learning from a variational data assimilation perspective. [PDF]

Sci Rep
Wang KY.
europepmc   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Phyllosphere microbiome responses to spray-induced gene silencing targeting Phytophthora infestans in potato. [PDF]

NPJ Biofilms Microbiomes
Ghosh S, Sundararajan P, Gelena Kelbessa B, Ghadamgahi F, Whisson SC, Dubey M, Chawade A, Vetukuri RR.   +7 more
europepmc   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Sex-differential associations of MC3R p.F45S with human metabolic profile. [PDF]

J Neuroendocrinol
Kaur TC, Wood AR, Hawkes G, Beaumont RN, Chundru K, Weedon MN, Piggins HD, Ellacott KLJ.   +7 more
europepmc   +1 more source

Meniscus‐Guided Interfacial Ring‐by‐Ring Assembly for In Situ Fabrication of Tubular Hydrogels

Advanced Materials, EarlyView.
A tubular hydrogel fabrication method leveraging the meniscus effect at the oil‐water interface is presented. UV irradiation across the concave surface of the photocurable hydrogel precursor induces the formation of ring‐like hydrogel structures. Sequential ring‐by‐ring assembly within microchannels enables the construction of arteriole‐scale hydrogel ...
Yuki Kamiya, Yingzhe Wang, Keisuke Morishima   +2 more
wiley   +1 more source

Maize variety traits for different needs: using the means-end chains method to identify preferences and perceived benefits among smallholder farmers in Kenya. [PDF]

Food Secur
Garcia-Medina M, Kilwinger F, Almekinders C, Donovan J.   +3 more
europepmc   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source

Aversive memory and extinction learning for noxious stimuli and aversive tastants in bumblebees. [PDF]

J Exp Biol
Sarlak S, Ashouri A, Goldansaz SH, MaBouDi H, Kleineidam C, Chittka L.   +5 more
europepmc   +1 more source

Food Colours

Journal of Synthetic Organic Chemistry, Japan, 1966
openaire   +2 more sources