Results 31 to 40 of about 25,774 (303)

Living in Food Deserts and Adverse Cardiovascular Outcomes in Patients With Cardiovascular Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Food deserts (FDs), defined as low‐income communities with limited access to healthy food, are a growing public health concern. We evaluated the impact of living in FDs on incident cardiovascular events.
Heval M. Kelli   +16 more
doaj   +1 more source

Introducing an innovative design to examine human-environment dynamics of food deserts responding to COVID-19

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2021
Food desert communities face persistent barriers in accessing affordable fresh and healthy foods, par­tic­ularly for the underserved and limited-resourced minority population.
Chyi-Lyi Liang   +6 more
doaj   +1 more source

Economic, Cultural, Social Determinants of Black Women Obesity [PDF]

open access: yesBusiness Ethics and Leadership
Obesity is a widespread problem in the United States, particularly affecting Black communities. It is a public health problem, a long-term, cumulative issue of economic and social justice and inequality for this demographic group.
Tiffiny Shockley, Darrell Norman Burrell
doaj   +1 more source

Assessing physical access to healthy food across United Kingdom: A systematic review of measures and findings

open access: yesObesity Science & Practice, 2022
Background Existing research suggests that physical access to food can affect diet quality and thus obesity rates. When defining retail food environment (RFE) quantitatively, there is a little agreement on how to measure “lack of healthy food” and what ...
Elzbieta Titis   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Desert tortoises (Gopherus agassizii) are selective herbivores that track the flowering phenology of their preferred food plants. [PDF]

open access: yesPLoS ONE, 2015
Previous studies of desert tortoise foraging ecology in the western Mojave Desert suggest that these animals are selective herbivores, which alter their diet according to the temporal availability of preferred food plants. These studies, however, did not
W Bryan Jennings, Kristin H Berry
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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