Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Message from the Department Head: Greetings, I write this in the quiet time between Christmas and New Year’s. I do not know if the Hokies will win their bowl game, but I do know this will be the 24th consecutive bowl appearance for Virginia Tech, the ...
Virginia Tech. Food Science and Technology Department
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
"Food For Thought"\ud Selected Design Installation\ud DIA Homegrown 2011 Life In the Slow Lane Exhibition: Little Stanley Street, South Bank, Brisbane [PDF]
'Homegrown is an initiative of the Design\ud Institute of Australia–Queensland Branch to\ud promote the collaboration and cultivation\ud of local design talent in Queensland and\ud strengthen the connection between design,\ud plate, planet, people and ...
Lindquist, Marissa +3 more
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3D Printing of Functional Strawberry Snacks: Food Design, Texture, Antioxidant Bioactive Compounds, and Microbial Stability. [PDF]
Bebek Markovinović A +11 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Handbook of Plant-Based Food and Drinks Design [PDF]
Handbook of Plant-Based Food and Drinks Design discusses conventional and emerging technologies for plant-based ingredient improvement (yield, nutritional composition and functional properties) while considering food safety, sustainability, and social ...
Rosell, Cristina M. +2 more
core +1 more source
Food Designs para el Pluriverso; desde enfoques participativos hasta el diseño de productos y servicios, los diseñadores replantean el pluriverso agroalimentario. : Food Designs for Pluriverse; From participatory approaches to product and service design, designers rethink the agri-food pluriverse. [PDF]
Este escrito presenta el número cuatro de la Revista Latinoamericana de Food Design: comes lo que eres. Inspirado en el concepto "comes lo que eres" este número incluye proyectos de investigación, reflexiones y otras aportaciones de la transdisciplina ...
Massari, Sonia
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Rational Food Design Targeting Micronutrient Deficiencies in Adolescents: Nutritional, Acoustic-Mechanical and Sensory Properties of Chickpea-Rice Biscuits. [PDF]
Talens C +3 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

