Results 61 to 70 of about 460,086 (309)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Challenges in the food supply chain following the great earthquake disaster in Turkey: A study of the regions of Malatya, Adıyaman and Kahramanmaraş

Journal of Education and Health Promotion
BACKGROUND: The consequences of natural disasters, such as damage to food systems, destruction of transport infrastructure, and organizational issues, can threaten the food security of people.
Hacer Alataş, Nurgül Arslan
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Infant and Young Child Feeding Practices Based on Region of Residence in Bengkulu Province, Indonesia

Amerta Nutrition
Background: Children under two years old go through a rapid physical growth period, requiring the highest nutritional intake compared to other age groups.
Demsa Simbolon, Desri Suryani, Yunita Yunita, Yusran Fauzi   +3 more
doaj   +1 more source

Food, Diversity, and Cultural Identity

Contingent Horizons: The York University Student Journal of Anthropology, 2022
The Rainbow Community Garden is a place for new immigrant and refugee families in Winnipeg to grow their own food. Using the Rainbow Community Garden as a case study, this paper contributes to ongoing discussions about community gardening by applying an anthropological lens to the multilayered meanings of agriculture in urban environments.
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Basic proposal for evaluation of plant genetic resources to generate new crops

Frontiers in Plant Science
Given the reduced diversity of foods available in production systems, a factor linked to malnutrition in society, it is necessary to evaluate new plant genetic resources for human consumption.
I. Darío Flores-Sánchez, Manuel Sandoval-Villa, Libia Iris Trejo-Téllez   +2 more
doaj   +1 more source

Chemical Multiverse and Diversity of Food Chemicals

Journal of Chemical Information and Modeling
Les produits chimiques alimentaires ont un rôle fondamental dans nos vies, avec un impact étendu sur la nutrition, la prévention des maladies et des implications économiques marquées dans l'industrie alimentaire. Le nombre de composés chimiques alimentaires dans les bases de données publiques a considérablement augmenté au cours des dernières années ...
Juan F. Avellaneda-Tamayo, Ana L. Chávez-Hernández, Diana L. Prado-Romero, José L. Medina-Franco   +3 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source