Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
Safety evaluation of the food enzyme pullulanase from the non-genetically modified <i>Klebsiella pneumoniae</i> strain AE-PUL. [PDF]
EFSA Panel on Food Enzymes (FEZ)+19 more
europepmc +1 more source
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee+10 more
wiley +1 more source
Safety evaluation of the food enzyme 4-α-glucanotransferase from the genetically modified <i>Bacillus amyloliquefaciens</i> strain MAS. [PDF]
EFSA Panel on Food Enzymes (FEZ)+18 more
europepmc +1 more source
Outcome of the Public Consultation on the Guidance of the Scientific Panel of Food Contact Material, Enzymes, Flavourings and Processing Aids (CEF) on Guidance on the data required for the risk assessment of flavourings to be used in or on foods [PDF]
openalex +1 more source
Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari+9 more
wiley +1 more source
Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified <i>Trichoderma citrinoviride</i> strain X31. [PDF]
EFSA Panel on Food Enzymes (FEZ)+20 more
europepmc +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme pectinesterase from the genetically modified <i>Trichoderma reesei</i> strain RF6201. [PDF]
EFSA Panel on Food Enzymes (FEZ)+15 more
europepmc +1 more source