In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang +14 more
wiley +1 more source
Safety evaluation of the food enzyme 4-α-glucanotransferase from the genetically modified <i>Bacillus amyloliquefaciens</i> strain MAS. [PDF]
EFSA Panel on Food Enzymes (FEZ) +18 more
europepmc +1 more source
The Effects of Enzyme Activation and Regeneration on Food Quality (Turkish with English Abstract)
Ahmet Yemenicioğlu, Bekir CEMEROĞLU
openalex +1 more source
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán +7 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme pectinesterase from the genetically modified <i>Trichoderma reesei</i> strain RF6201. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico +8 more
wiley +1 more source
Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified <i>Trichoderma citrinoviride</i> strain X31. [PDF]
EFSA Panel on Food Enzymes (FEZ) +20 more
europepmc +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
Safety evaluation of the food enzyme phospholipase A1 from the genetically modified <i>Trichoderma reesei</i> strain DP-Nzk98. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source

