Results 121 to 130 of about 4,162,866 (313)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Markets Need Predictable Government Actions to Function Effectively: The Case of Importing Maize in Times of Deficit [PDF]

open access: yes
Food relief for vulnerable groups is important in times of deficit. For the remainder of the population, well functioning grain markets can save lives during times of food shortfalls.
Jayne, Thomas S.   +3 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

An Analysis of the Consumption of Sausages in Scotland using Supermarket Data [PDF]

open access: yes
This paper addresses consumers’ choices by looking into: current food choices made by different socio-economic groups; price barriers for diet improvement; and ways in which marketing may affect product choice.
Davis, Victoria   +5 more
core   +4 more sources

The Food Groups of MyPyramid

open access: yesEDIS, 2009
FCS-8873, a 2-page illustrated fact sheet by Glenda L. Warren, lists each of the food groups, with descriptions and examples, and a key message for each group. Published by the UF Department of Family Youth and Community Sciences, December 2008. December 2019 reprint of 2008 content.
openaire   +3 more sources

Consumers' Perception of Food-System Vulnerability to an Agroterrorist Attack [PDF]

open access: yes
This paper uses results from a 2004 survey (N=1,010) on consumer attitudes toward agroterrorism and food-system security to investigate heterogeneous attributes affecting vulnerability including risk perceptions and fear.
Condry, Sarah C.   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Do Statin Users Adhere to Dietary Recommendations for Cardiovascular Disease Prevention?

open access: yesProceedings
Emerging evidence suggests that there is an interplay between the effects of diet and lipid-lowering therapy in primary and secondary prevention of cardiovascular disease. All prevention strategies focus on modifiable risk factors, with special attention
Milica Zrnic Ciric   +6 more
doaj   +1 more source

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