Results 51 to 60 of about 223,154 (323)

Novel Gut Microbiota Patterns Involved in the Attenuation of Dextran Sodium Sulfate-Induced Mouse Colitis Mediated by Glycerol Monolaurate via Inducing Anti-inflammatory Responses

mBio, 2021
The gut microbiota, which can be highly and dynamically affected by dietary components, is closely related to IBD pathogenesis.
Qiufen Mo, Tao Liu, Aikun Fu, Shengyue Ruan, Hao Zhong, Jun Tang, Minjie Zhao, Yang Li, Songming Zhu, Haiying Cai, Fengqin Feng   +10 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Multistate Shigellosis Outbreak and Commercially Prepared Food

Emerging Infectious Diseases, 2004
In 2000, shigellosis traced to a commercially prepared dip developed in 406 persons nationwide. An ill employee is suspected to have inadvertently contaminated processing equipment.
Akiko C. Kimura, Kammy Johnson, Mary S. Palumbo, Jacqueline Hopkins, Janice C. Boase, Roshan Reporter, Marcia Goldoft, Karen R. Stefonek, Jeff A. Farrar, Thomas J. Van Gilder, Duc J. Vugia   +10 more
doaj   +1 more source

Cook-Gen: Robust Generative Modeling of Cooking Actions from Recipes [PDF]

arXiv, 2023
As people become more aware of their food choices, food computation models have become increasingly popular in assisting people in maintaining healthy eating habits. For example, food recommendation systems analyze recipe instructions to assess nutritional contents and provide recipe recommendations. The recent and remarkable successes of generative AI
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Classification of Strawberry Maturity Stages and Varieties Using Neural Networks Based on Volatile Organic Compounds

Foods
Volatile organic compounds (VOCs) are closely associated with the maturity and variety of strawberries. However, the complexity of VOCs hinders their potential application in strawberry classification. This study developed a novel classification workflow
Jing Huang, Xuenan Zhang, Hang Yang, Zhenbiao Li, Zhengfang Xue, Qingqing Wang, Xinyuan Zhang, Shenghua Ding, Zisheng Luo, Yanqun Xu   +9 more
doaj   +1 more source

Adaptive Collective Responses to Local Stimuli in Anonymous Dynamic Networks [PDF]

arXiv, 2023
We develop a framework for self-induced phase changes in programmable matter in which a collection of agents with limited computational and communication capabilities can collectively perform appropriate global tasks in response to local stimuli that dynamically appear and disappear.
arxiv  

Personalized Classifier for Food Image Recognition [PDF]

IEEE Transactions on Multimedia 20.10 (2018): 2836-2848, 2018
Currently, food image recognition tasks are evaluated against fixed datasets. However, in real-world conditions, there are cases in which the number of samples in each class continues to increase and samples from novel classes appear. In particular, dynamic datasets in which each individual user creates samples and continues the updating process often ...
arxiv   +1 more source