Clinical Pharmacology in Drug Development, EarlyView.Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch +9 more
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FURTHER OBJECTIVE STUDIES IN CHILDREN WITH HYPERSENSITIVITY TO FOODS [PDF]
, 1977 S. Allan Bock, Charles D. May
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Doppler Ultrasonographic Evaluation of Gastrointestinal Hemodynamics in Food Hypersensitivities: A Canine Model [PDF]
, 2004 Patrick R. Kircher +5 more
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Clinical Pharmacology in Drug Development, EarlyView.Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye +8 more
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Session 1: Allergic disease The challenges of managing food hypersensitivity [PDF]
, 2009 Carina Venter, Rosan Meyer
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Clinical Pharmacology in Drug Development, EarlyView.Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
A Safe and Effective Method for Wheat Oral Immunotherapy
Iranian Journal of Allergy, Asthma and Immunology, 2017 At present the only available management for food allergy is avoidance; however, abstaining from allergic foods can affect the quality of life. Oral Immunotherapy (OIT) is an efficient method for increasing tolerance towards food allergens.
Alireza Khayatzadeh +4 more
doaj
Prevalence of Food-Hypersensitivity and Food-Dependent Anaphylaxis in Colombian Schoolchildren by Parent-Report. [PDF]
Medicina (Kaunas), 2021 Beltrán-Cárdenas CE +8 more
europepmc +1 more source
Exploring the relationship between dietary patterns, eating behaviour and fat taste detection thresholds : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Nutrition and Dietetics at Massey University, Albany, New Zealand [PDF]
, 2016 Background: Dietary pattern analysis provides a unique opportunity to explore combinations of food intake in conjunction with factors known to affect dietary intake. Fat taste sensitivity is an emerging correlate of dietary intake and, when impaired, has
Henderson, Lisa
core
Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?
Clinical Pharmacology &Therapeutics, EarlyView.Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart +6 more
wiley +1 more source