Results 151 to 160 of about 150,738 (301)

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura   +11 more
wiley   +1 more source

Large Hydatid Cyst in the Cardiac Interventricular Septum: A Rare Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, EarlyView.
Hydatid disease is a parasitic disease with a high incidence in pastoral areas in Tibet. The heart is an uncommon location of echinococcosis, and involvement of the interventricular septum is even rarer. This disease can remain asymptomatic for a long time, but may result in cardiac tamponade and sudden death.
Lin Gao, Yixiu Zhang, Xiao Yang
wiley   +1 more source

Oral and dental status in children with intestinal failure: A descriptive cross‐sectional study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure often experience feeding difficulties and complex daily care needs, yet their oral and dental health remains underexplored. We aimed to describe oral and dental health characteristics in pediatric intestinal failure.
Anat Guz‐Mark   +3 more
wiley   +1 more source

Antibiotics in the first week of life are not associated with functional gastrointestinal disorders at 9–12 years of age

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1400-1407, June 2026.
Abstract Objectives Dysbiosis due to early‐life antibiotics may contribute to the development of functional gastrointestinal disorders (FGIDs). This follow‐up study of a birth cohort primarily investigates the association between antibiotic treatment in the first week of life and the presence of FGIDs at 9–12 years.
Nora C. Carpay   +3 more
wiley   +1 more source

European Society for Paediatric Gastroenterology, Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines for treatment of functional constipation in children aged 0–18 years

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Functional constipation (FC) is common in childhood, significantly impacting quality of life. Since the 2014 international guideline, new evidence has been published, and methods on making guidelines have developed. This treatment guideline for FC in children aged 0–18 years is a collaborative effort of the European and North ...
Morris Gordon   +17 more
wiley   +1 more source

Feasibility and efficacy of fecal microbiota transplantation in adolescents with refractory irritable bowel syndrome: A randomized clinical pilot trial

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To assess the feasibility and efficacy of fecal microbiota transplantation (FMT) in adolescents (16–21 years) with refractory irritable bowel syndrome (IBS). Methods Randomized controlled pilot trial. Thirty‐two patients were included and randomized to receive two allogeneic or autologous FMTs.
Clara M. A. de Bruijn   +8 more
wiley   +1 more source

Functional constipation in children and young adults with Prader–Willi syndrome

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Prader–Willi Syndrome (PWS) is characterized by hyperphagia, endocrinopathies, and gastrointestinal abnormalities. Clinical concerns about constipation and fecal incontinence (FI) are common, but no studies to date have clear data on functional defecation disorders in children with PWS.
Melinda J. Pierce   +3 more
wiley   +1 more source

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