Results 191 to 200 of about 2,536,282 (288)

Electrocardiograpic responses during spontaneous hypoglycaemia in people with type 1 diabetes and impaired awareness of hypoglycaemia

Diabetic Medicine, EarlyView.
Abstract Aims Hypoglycaemia causes abnormal cardiac repolarisation, which has been related to sympathoadrenal activation. We examined whether individuals with type 1 diabetes (T1D) and impaired awareness of hypoglycaemia (IAH) were protected against proarrhythmogenic alterations on their electrocardiogram during clinical episodes of hypoglycaemia ...
Peter Novodvorsky, Alan Bernjak, Ellen Downs, Amelia Smith, Muhammad Fahad Arshad, Andrei I. Oprescu, Richard M. Jacques, Justin Lee, Simon R. Heller, Ahmed Iqbal   +9 more
wiley   +1 more source

Editorial: Women in science: allergy research. [PDF]

Front Allergy
Carreras-Badosa G, Esteban V, Hernandez-Trujillo V, Toskala E, Mukherjee M, Al Heialy S, Fieten K.   +6 more
europepmc   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Olanzapine-induced Drug Reaction with Eosinophilia and Systemic Symptoms: Case Report and Review of the Literature. [PDF]

Acta Derm Venereol
Ickrath K, Kneitz H, Schmieder A, Goebeler M, Stoevesandt J.   +4 more
europepmc   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

The FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika, Antonia Paić, Ana Novačić, Tea Martinić Cezar, Béatrice Vallée, Renata Teparić, Igor Stuparević, Bojan Žunar   +7 more
wiley   +1 more source

Clinical characteristics and risk factors for escalation to anaphylaxis from non-severe drug hypersensitivity reaction. [PDF]

Clin Transl Allergy
Rhyou HI, Kim SR, Jung JW, Kim SH, Lee JH, Park HJ, Park KH, Park HS, Chung EH, Choi GS, Kim S, Yang MS, Shim JY, Koh YI, Sim DW, Lee JH, Nam YH, Kang HR.   +17 more
europepmc   +1 more source

Characterising Lipid Transfer Protein Allergy in UK Adults

Clinical &Experimental Allergy, EarlyView.
I. J. Skypala, B. Olivieri, G. Scadding
wiley   +1 more source

A Systematic Review Evaluating Methods for Diagnosis, Treatment and Prevention of Dental Erosions

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Aim The aim of this systematic review was to investigate the quality of evidence for methods used to diagnose, restore and prevent dental erosions, by evaluating and summarising clinical controlled studies and in situ studies covering this field.
Maria Skalsky Jarkander, Helena Domeij, Irene Edebert, Alfheidur Astvaldsdottir, Margaret Grindefjord, Annsofi Johannsen   +5 more
wiley   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source