Results 201 to 210 of about 3,075,206 (240)

Severity of irritable bowel syndrome and its correlates among Middle East and North African medical students: a multicentric cross sectional study. [PDF]

Sci Rep
Abdelshafi A, Abdelhamid ZG, Osama B, Mohammed YA, Allam N, Youssef YG, Abdul-Hafez HA, Sabbagh S, Yakout IA, Aljarad Z, Osman DM, Abdel-Salam DM.   +11 more
europepmc   +1 more source

Efficacy and Safety of Abatacept Versus Placebo During Peanut Oral Immunotherapy for Adults With Severe Peanut Allergy

Allergy, EarlyView.
In this Phase 2a trial, severely peanut‐allergic participants were randomized to abatacept versus placebo with peanut oral immunotherapy (OIT) for 24 weeks, followed by 12 weeks of OIT alone. No significant difference was observed for the primary efficacy outcome (the relative change from baseline in peanut‐specific/total IgE ratio at 24 weeks), but ...
Marie‐Lee Simard, Camille Braun, Éloise Antony, Émilie Roy, Marie‐Ève Gingras, François Graham, Anne Des Roches, Louis Paradis, Kathryn Samaan, Florence Gingras‐Lessard, Roxane Labrosse, Thomas Eiwegger, Philippe Bégin   +12 more
wiley   +1 more source

European Guidelines on Eosinophilic Esophagitis: Evidence‐Based Statements and Recommendations for Diagnosis and Management in Children and Adults. Part 1: Diagnosis, Epidemiology and Natural History

Allergy, EarlyView.
The European evidence‐based guidelines on eosinophilic esophagitis (Part 1). This infographic summarizes the methodological framework and core clinical outputs of the updated consensus developed by multidisciplinary experts from EUREOS, EAACI, ESPGHAN, and ESP.
Alfredo J. Lucendo, Javier Molina‐Infante, Ángel Arias, Ulrike von Arnim, Henrik Bergquist, Luc Biedermann, Albert J. Bredenoord, Marie Carlson, Javier Chahuan, Jorge Amil Dias, Thomas Eiwegger, Sara Feo‐Ortega, Sandra L. Garcia‐Dionisio, Matteo Ghisa, Jesús González‐Cervera, Thomas Greuter, Danila Guagnozzi, Carolina Gutiérrez‐Junquera, Lucía Gutiérrez‐Ramírez, Cord Langner, Helen Larsson, Anne Lund Krarup, Salvatore Oliva, Alexandra Papadopoulou, Francesca Racca, Cecilio Santander, Edoardo Vincenzo Savarino, Christoph Schlag, Alain M. Schoepfer, Martin A. Storr, Antonio Tejera‐Muñoz, Noam Zevit, Stephen E. Attwood, Alex Straumann   +33 more
wiley   +1 more source

Chia Seed Allergy: Emerging Clinical Evidence, Molecular Allergens, and the Unresolved Question of Cross-Reactivity. [PDF]

Nutrients
Porr C, Vidrighin A, Catana AC, Preda EM, Iovin VC, Iancu GM, Harris DM, Diaconu C.   +7 more
europepmc   +1 more source

Contamination of Drinking Water and Food With Contrast Media, and How We Could Omit This: A Hint Using RadioComics

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Ingrid Boehm
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics. [PDF]

Clin Pharmacol Ther
Pinnow E, Day B, Zhou EH, Woods C, Dwumfour N, Lee JY, Bulatao I, Cherkaoui S, Kalaria M, Brajovic S, Sadiq N, Sistani F, Lee M, Chai G, Dal Pan G.   +14 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

How Are Plant-Based Milk Alternatives Presented Online? A Comparison of Information on Allergens, Nutrients and Sustainability Between Product Types From Selected UK Retailer Websites. [PDF]

Food Sci Nutr
Bula MJ, Wallis LW, Arrowsmith HE, James CA, Moore S, Thondre PS.   +5 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source