Results 201 to 210 of about 2,663,399 (366)

Design and Synthesis of Polyamine‐Proteolysis Targeting Chimera Conjugates for Histone Deacetylase (HDAC) Degradation with Enhanced Cellular Uptake

ChemistryOpen, EarlyView.
In this article, proteolysis targeting chimeras (PROTACs) bearing a polyamine linker capable of crossing cancer cell membranes via the polyamine transport system are synthesized and evaluated. The results provide valuable insights for the design of PROTACs with enhanced cellular uptake efficiency.
Yanran Liu, Wentian Chen, Yanwei Shang, Chaonan Tang, Xianming Zeng, Jun Li, Wenting Du   +6 more
wiley   +1 more source

Subjective food hypersensitivity: Lifestyle and psychological factors [PDF]

, 2010
Ragna Lind
openalex  

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Serumanti-Gliadin IgA Antibody (AAG-IgA) and D-Xylose Absorption Test for Differential Diagnosis of Celiac Disease (CD) and Food Hypersensitivity (FH) [PDF]

, 1996
Ceres Concílio Romaldini, Donatella Barbieri, F R Carraza   +2 more
openalex   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Effects of probiotics in the treatment of food hypersensitivity in children: a systematic review

, 2019
Stephanie Campos dos Santos, Túlio Konstantyner, Renata Rodrigues Cocco   +2 more
openalex   +1 more source

Food hypersensitivity in patients treated with specific allergen immunotherapy (SIT) for aeroallergens [PDF]

, 2013
Jacek Gocki, Zbigniew Bartuzi
openalex   +1 more source

Latent Profile Analysis of Sleep Patterns in Children With Autism Spectrum Disorder

Pediatric Discovery, EarlyView.
Children with autism spectrum disorder (ASD) exhibited three distinct sleep phenotypes. Cluster 3, characterized by mild sleep‐disordered breathing, showed significant improvements in core symptoms, whereas Clusters 1 and 2 demonstrated modest changes.
Ke Wang, Qiuhong Wei, Ting Yang, Feiyong Jia, Yan Hao, Jinchen Li, Jie Chen, Tingyu Li, Hongyu Chen, Ximing Xu   +9 more
wiley   +1 more source

Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics

Pest Management Science, EarlyView.
Microphenomics is a new technique for detecting the very early resistance of powdery mildew in wheat seedlings, after 24, 48, and 72 h from infection. A number of 29, 42, and 34 genes models were identified to harbor significant SNP markers associated with the early resistance to WPM.
Amira M.I. Mourad, Hanaa M.S. Ibrahim, Stefanie Lück, Andreas Börner, Dimitar Douchkov   +4 more
wiley   +1 more source

Salicylic acid: a key natural foundation for next‐generation plant defense stimulators

Pest Management Science, EarlyView.
Salicylic acid is emerging as a key natural molecule in sustainable crop protection, supporting diverse strategies to stimulate and sustain plant immunity for a greener agricultural future. Abstract The field of crop protection is undergoing a major transition.
Ruth Oussou, Sylvain La Camera, Cécile Marivingt‐Mounir, Jean‐François Chollet   +3 more
wiley   +1 more source