Results 61 to 70 of about 2,176,820 (312)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Research progress on rapeseed green processing technology

open access: yesLiang you shipin ke-ji, 2020
Green processing technology has wide prospects in rapeseed industry.The research progress of process technologies including microwave, pulsed electric field, shelling, cold pressing, enzymatic hydrolysis,supercritical CO2 extraction, low temperature ...
ZHANG Xin   +6 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Effect of formulation of pumpkin and yellow sweet potato flour on the physicochemical and sensory characteristics of instant cream soup [PDF]

open access: yesBIO Web of Conferences
Pumpkin (Cucurbita moschata) can be processed into instant soup. Yellow sweet potato flours can be added to pumpkin instant cream soup which are beneficial for the health of the body when consumed. This study aimed to investigate the effects of different
Putri Amanda Lili Andini   +2 more
doaj   +1 more source

Globalization of Slovenian Agricultural and Food Trade [PDF]

open access: yes
This paper analyses globalization patterns in the Slovenian agricultural and food trade. It examines prevailing trade structures and trade types to study differences and similarities in trade specialization patterns between primary and processed ...
Darja Majkovic, Stefan Bojnec
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effect of the combined action of myofibrillar protein phosphorylation and S-nitrosylation on the degradation of myofibrillar proteins by µ-calpain

open access: yesFood Science of Animal Resources
This study investigated the responsiveness of interactively phosphorylated and S-nitrosylated myofibrillar proteins (MPs) to µ-calpain for elucidating the interactive effect of phosphorylation and S-nitrosylation on MPs degradation.
Manting Du   +6 more
doaj   +1 more source

Anti-aging effect of hydrocolloid on tartary buckwheat parfaith

open access: yesLiang you shipin ke-ji, 2019
The effects of mono-hydrophilic colloid(xanthan gum,guar gum,sodium alginate,hydroxypropyl methylcellulose and carrageenan) on the anti-aging of tartary buckwheat parfait were studied with sensory evaluation and hardness as indexes,and three kinds of ...
BAI Ju-hong   +6 more
doaj   +1 more source

Agglomeration Effects and Japanese Food Industry Investment in China: Evidence from the Cities [PDF]

open access: yes
This paper uses the data from Chugoku Shinshutsu Kigyou Ichiran 2003-2004 (A View of Japanese Enterprises Investments in China 2003-2004) to study 1ocation choice of Japanese food industry investment in 231 Chinese cities from 1992 to 2001, paying a ...
Akune, Yuko   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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