Results 41 to 50 of about 100,181 (257)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Effect of various processing factors on the pH, water activity and microbiological characteristics of pickled Japanese quail (Coturnix c, japonica) eggs

Journal of Applied Poultry Research
Summary: This study determined the effect of different commercial pickling errors on pH, water activity and microbiology of hard cooked quail eggs. Experiment 1 tested pH and water activity of cooled and hot hard cooked eggs held for 24 or 48 h in tap ...
A. Hoover, P.L. Dawson, D.P. Smith, J.K. Northcutt   +3 more
doaj   +1 more source

Scientific Opinion on the safety evaluation of the active substance, open‐cell expanded polystyrene manufactured with talc and alkyl(C8‐C22) sulphonic acid (salts)for use in active food contact materials

EFSA Journal, 2012
This scientific opinion of EFSA deals with the risk assessment of the open‐cell expanded polystyrene, manufactured with talc, CAS No 14807‐96‐6, FCM substance No 615, and alkyl(C8‐C22) sulphonic acid (salts) FCM substance No 16.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Food ingredients and packaging unit (FIP)   +1 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

CHEMICAL COMPOSITION OF HONEYBEE (Apis mellifera L.) BROOD [PDF]

Journal of Plant Protection and Pathology, 2009
Brood of honeybees (larvae & pupae), was periodically collected at 15 day intervals from the bee hives. The chemical components of these brood were determined and compared with the familiar protein sources.
Enas. Nour El-Din, Manal Sorour, M. Abd Al-Fattah   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Innovative Systems for the Delivery of Naturally Occurring Antimicrobial Volatiles in Active Food-Packaging Technologies for Fresh and Minimally Processed Produce: Stimuli-Responsive Materials

Foods
Certain naturally occurring volatile organic compounds are able to mitigate food spoilage caused by microbial growth. Their considerable vapor pressure enables them to create an antimicrobial atmosphere within a package, and this property can be used for
Patricia Esteve-Redondo, Raquel Heras-Mozos, Ernest Simó-Ramírez, Gracia López-Carballo, Carol López-de-Dicastillo, Rafael Gavara, Pilar Hernández-Muñoz   +6 more
doaj   +1 more source