Results 41 to 50 of about 95,904 (256)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of various processing factors on the pH, water activity and microbiological characteristics of pickled Japanese quail (Coturnix c, japonica) eggs

Journal of Applied Poultry Research
Summary: This study determined the effect of different commercial pickling errors on pH, water activity and microbiology of hard cooked quail eggs. Experiment 1 tested pH and water activity of cooled and hot hard cooked eggs held for 24 or 48 h in tap ...
A. Hoover, P.L. Dawson, D.P. Smith, J.K. Northcutt   +3 more
doaj   +1 more source

CHEMICAL COMPOSITION OF HONEYBEE (Apis mellifera L.) BROOD [PDF]

Journal of Plant Protection and Pathology, 2009
Brood of honeybees (larvae & pupae), was periodically collected at 15 day intervals from the bee hives. The chemical components of these brood were determined and compared with the familiar protein sources.
Enas. Nour El-Din, Manal Sorour, M. Abd Al-Fattah   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Scientific Opinion on the safety evaluation of the active substance, open‐cell expanded polystyrene manufactured with talc and alkyl(C8‐C22) sulphonic acid (salts)for use in active food contact materials

EFSA Journal, 2012
This scientific opinion of EFSA deals with the risk assessment of the open‐cell expanded polystyrene, manufactured with talc, CAS No 14807‐96‐6, FCM substance No 615, and alkyl(C8‐C22) sulphonic acid (salts) FCM substance No 16.
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Food ingredients and packaging unit (FIP)   +1 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Innovative Systems for the Delivery of Naturally Occurring Antimicrobial Volatiles in Active Food-Packaging Technologies for Fresh and Minimally Processed Produce: Stimuli-Responsive Materials

Foods
Certain naturally occurring volatile organic compounds are able to mitigate food spoilage caused by microbial growth. Their considerable vapor pressure enables them to create an antimicrobial atmosphere within a package, and this property can be used for
Patricia Esteve-Redondo, Raquel Heras-Mozos, Ernest Simó-Ramírez, Gracia López-Carballo, Carol López-de-Dicastillo, Rafael Gavara, Pilar Hernández-Muñoz   +6 more
doaj   +1 more source