Results 51 to 60 of about 799,910 (289)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Functional food consumption preference in Culiacán, Mexico

Salud Pública de México
Objective. To determine functional food consumption preferences in Culiacán, Mexico. Materials and methods. A survey was designed, validated, and implemented to gather information on functional food consumption. Associations between health conditions and
Fernando López-Cardoso, Noe Ontiveros-Apodaca, Erick Paul Gutiérrez-Grijalva, Jesús Gilberto Arámburo-Gálvez, Oscar Gerardo Figueroa-Salcido, Nayely Leyva-López, Diego A Gastélum-Chavira, Feliznando Isidro Cárdenas-Torres, J Basilio Heredia   +8 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Conditioned food preferences [PDF]

Bulletin of the Psychonomic Society, 1991
Animals learn to prefer the flavors of foods on the basis of the foods’ postingestive nutritional consequences. This has been demonstrated with the conditioned flavor preference paradigm. With this paradigm, one flavor (the CS+) is paired with a nutrient that is orally consumed or is infused via a post-oral (e.g., intragastric) route; another flavor ...
openaire   +2 more sources

Reversing food preference through multisensory exposure

PLOS ONE, 2023
Experiencing food craving is nearly ubiquitous and has several negative pathological impacts prompting an increase in recent craving-related research. Food cue-reactivity tasks are often used to study craving, but most paradigms ignore the individual food preferences of participants, which could confound the findings. We explored the neuropsychological
Avishek Chatterjee, Satyaki Mazumder, Koel Das   +2 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Cognitive and preference disparities of Chinese consumers regarding the disclosure of unsafe food recall information

Frontiers in Public Health
IntroductionInformation disclosure is important in promoting unsafe food recalls and reducing potential food safety risks. However, the governance of unsafe food recall information in China is distorted, leading to cognitive dissonance in Chinese ...
Taiping Li, Xiaohui Jin, Daocai Zhu
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Factores asociados a las preferencias alimentarias de los niños [PDF]

Eleuthera, 2018
Objective. The main objective is to introduce a literature review of the influence of families and schools on children’s food preferences and to understand those factors associated with children´s food preferences. Methodology. An analysis of information
Sugey Elena Anaya-García, Mónica María Álvarez-Gallego   +1 more
doaj   +1 more source