Results 41 to 50 of about 138,433 (259)

Food Calls in Common Marmosets, Callithrix jacchus, and Evidence That One Is Functionally Referential

open access: yesAnimals, 2018
We studied three calls of common marmosets, Callithrix jacchus, elicited in the context of food. Call A, but not B or C, had been described previously as a food call. We presented insects (live mealworms or crickets) and fruit (banana or blueberries) and
Lesley J. Rogers   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Functional food consumption preference in Culiacán, Mexico

open access: yesSalud Pública de México
Objective. To determine functional food consumption preferences in Culiacán, Mexico. Materials and methods. A survey was designed, validated, and implemented to gather information on functional food consumption. Associations between health conditions and
Fernando López-Cardoso   +8 more
doaj   +1 more source

Patterning of food preferences among iranian adults: Results from SEPAHAN study

open access: yesInternational Journal of Preventive Medicine, 2020
Background: The present study was conducted to evaluate the pattern of food preference among a large sample of Iranian adults. Methods: In a cross-sectional study within the study on the epidemiology of psychological alimentary health and nutrition ...
Maedeh Moradi   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Influence of eating while watching TV on food preference and overweight/obesity among adolescents in China: a longitudinal study

open access: yesFrontiers in Public Health
BackgroundEating while watching TV was found associated with unhealthy food preferences and obesity in adolescents in foreign studies, which is not clear in China.
Jinli Xian, Tingwei Ren, Ming Kuang
doaj   +1 more source

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