Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Hydrogel-based systems with nanoparticle and microencapsulation for food preservation: Preparation, characterization, and application. [PDF]
Zhou H +9 more
europepmc +1 more source
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Active Antimicrobial Packaging Systems: Mechanisms of Microbial Control and Applications in Food Preservation. [PDF]
Pérez E +6 more
europepmc +1 more source
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto +10 more
wiley +1 more source
Research review of enzyme-responsive packaging in food preservation. [PDF]
Jiang C, Hao Y, Jin Z, Liu J, Sun W.
europepmc +1 more source
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull +11 more
wiley +1 more source
Bee products in biopolymer films/coatings: Advancing sustainable active packaging for food preservation. [PDF]
Li X +6 more
europepmc +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Effect of pH on recovery efficiency and anthocyanin composition of <i>Clitoria ternatea</i> extracts with application as lipid antioxidants in food preservation. [PDF]
Nguyen KD, Tran TTT, Le NA, Dong TAD.
europepmc +1 more source

