Results 31 to 40 of about 6,442,183 (298)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Technical efficiency of the food and drink industry and its determinants

Agricultural Economics (AGRICECON), 2021
This study focuses on evaluating the technical efficiency (TE) of food and drink companies in the Czech Republic and on finding its determinants. The analysis is based on the data of 597 firms and uses the stochastic frontier method.
Zdeňka Náglová, Marie Šimpachová Pechrová   +1 more
doaj   +1 more source

Drivers of food safety adoption among food processing firms: A nationally representative survey in Ghana

, 2020
Globally, food system transformation is characterized by the increasing importance of food safety and quality standards for consumers. This trend is challenging for the food processing sector in Ghana, which is dominated by micro and small firms.
http://orcid.org/0000-0001-5960-3189 Asante, Seth; http://orcid.org/0000-0002-8033-0784 Ragasa, Catherine; http://orcid.org/0000-0002-4138-1693 Andam, K., Asante, Seth B.; Ragasa, Catherine; Andam, Kwaw S., Seth B. Asante, Catherine Ragasa,, Kwaw S. Andam   +4 more
core   +1 more source

Corporate R&D and the performance of food-processing firms: Evidence from Europe, Japan and North America [PDF]

, 2020
This paper investigates the impact of corporate research and development (R&D) on firm performance in the food-processing industry. We apply Data Envelopment Analysis (DEA) with two step bootstrapping using a corporate data for 307 food-processing firms ...
Hockmann, Heinrich, Voigt,Peter, Gomez y Paloma, Sergio, Delvaux, Pedro Andres Garzon, Ciaian, Pavel   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Subsidies and technical efficiency of Czech food processing industry

Agricultural Economics (AGRICECON), 2019
At present, the New Common Agricultural Policy for the period 2021-2027 has been currently formulated. Future of the agriculture and food industry is now widely discussed.
Zdeňka Náglová, Marie Šimpachová Pechrová   +1 more
doaj   +1 more source

Determinants influencing the profitability of listed food processing firms in Vietnam

Accounting, 2020
Cette recherche est menée pour évaluer les déterminants influençant la rentabilité des entreprises de transformation alimentaire au Vietnam. Les données ont été collectées à partir des états financiers audités des entreprises de transformation alimentaire cotées à la Bourse du Vietnam de 2012 à 2018 et le modèle de régression du panel a été utilisé ...
Huy Bui, Duc Viet Nguyen, Do Duc Manh Tran, Phuong Thao Hoang, Minh Huong Pham, Mạnh Dũng Trần, Bui Huy Nhuong   +6 more
openaire   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source